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Dr Libby Ellins

Senior Vascular Scientist / Research Manager

Health Data Science

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Available For Postgraduate Supervision

Research Links

https://orcid.org/0000-0001-5164-6416

About

Dr Ellins’ is a vascular scientist with an interest in the understanding of the development of cardiovascular disease through the use of non-invasive methods for the assessment of vascular structure and function. In addition, she also has an interest in the interplay between mental health and cardiovascular disease development and outcomes and is exploring these relationships through the SAIL databank.

Areas Of Expertise

Non-invasive assessment of vascular structure and function
Cardiovascular disease and mental health

Publications

Research Highlights

Ellins, L., Wareham, K., Harris, D., Hanney, M., Akbari, A., Gilmore, M., Barry, J., Phillips, C., Gravenor, M., & Halcox, J. (2023). Incident atrial fibrillation and adverse clinical outcomes during extended follow-up of participants recruited to the remote heart rhythm sampling using the AliveCor heart monitor to screen for atrial fibrillation: the REHEARSE-AF study. European Heart Journal Open, 3(3)
https://doi.org/10.1093/ehjopen/oead047, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63344
http://dx.doi.org/10.1093/ehjopen/oead047
McKechnie, D., Patel, M., Papacosta, A., Lennon, L., Ellins, L., Halcox, J., Ramsay, S., Whincup, P., & Wannamethee, S. (2022). Associations between inflammation, coagulation, cardiac strain and injury, and subclinical vascular disease with frailty in older men: a cross-sectional study. BMC Geriatrics, 22(1)
https://doi.org/10.1186/s12877-022-03106-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59916
Ellins, L., Harris, D., Lacey, A., Akbari, A., Torabi, F., Smith, D., Jenkins, G., Obaid, D., Chase, A., John, A., Gravenor, M., & Halcox, J. (2022). Achievement of European Society of Cardiology/European Atherosclerosis Society lipid targets in very high-risk patients: Influence of depression and sex. PLOS ONE, 17(2), e0264529
https://doi.org/10.1371/journal.pone.0264529, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59420
McKechnie, D., Papacosta, A., Lennon, L., Ellins, L., Halcox, J., Ramsay, S., Whincup, P., & Wannamethee, S. (2021). Subclinical cardiovascular disease and risk of incident frailty: The British Regional Heart Study. Experimental Gerontology, 154, 111522
https://doi.org/10.1016/j.exger.2021.111522, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57624
Murray, R., Kitaba, N., Antoun, E., Titcombe, P., Barton, S., Cooper, C., Inskip, H., Burdge, G., Mahon, P., Deanfield, J., Halcox, J., Ellins, L., Bryant, J., Peebles, C., Lillycrop, K., Godfrey, K., Hanson, M., & Consortium), . (2021). Influence of Maternal Lifestyle and Diet on Perinatal DNA Methylation Signatures Associated With Childhood Arterial Stiffness at 8 to 9 Years. Hypertension, 78(3), 787-800.
https://doi.org/10.1161/hypertensionaha.121.17396, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56995
http://dx.doi.org/10.1161/hypertensionaha.121.17396
McNarry, M., Lester, L., Ellins, L., Halcox, J., Davies, G., Winn, C., & Mackintosh, K. (2021). Asthma and high-intensity interval training have no effect on clustered cardiometabolic risk or arterial stiffness in adolescents. European Journal of Applied Physiology, 121(7), 1967-1978.
https://doi.org/10.1007/s00421-020-04590-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56651
Ellins, L., Watkins, S., Rees, D., Datta, D., & Halcox, J. (2021). Acute effect of a single session of lipoprotein apheresis on central haemodynamics in patients with familial hypercholesterolaemia. Atherosclerosis, 325, 121-123.
https://doi.org/10.1016/j.atherosclerosis.2021.03.023, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56504
http://dx.doi.org/10.1016/j.atherosclerosis.2021.03.023
Marshall, Z., Mackintosh, K., Lewis, M., Ellins, L., & McNarry, M. (2021). Association of physical activity metrics with indicators of cardiovascular function and control in children with and without type 1 diabetes. Pediatric Diabetes, 22(2), 320-328.
https://doi.org/10.1111/pedi.13159, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55673
Davies, R., Williams, J., Sime, K., Jin, H., Thompson, C., Jordan, L., Lang, D., Halcox, J., Ellins, E., Jones, G., Jones, S., Rose-John, S., Williams, A., Choy, E., Halcox, J., & Ellins, L. (2021). The role of interleukin-6 trans-signalling on cardiovascular dysfunction in inflammatory arthritis. Rheumatology, 60(6), 2852-2861.
https://doi.org/10.1093/rheumatology/keaa725, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55470
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., Demmler, J., McCoubrey, S., Halcox, J., Audrey, S., Ellins, L., & Brophy, S. (2020). Active Children Through Individual Vouchers Evaluation: A Mixed-Method RCT. American Journal of Preventive Medicine, 58(2), 232-243.
https://doi.org/10.1016/j.amepre.2019.10.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52367
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., Demmler, J., McCoubrey, S., Halcox, J., Audrey, S., Ellins, L., & Brophy, S. (2019). Predictors of cardiovascular health in teenagers (aged 13–14 years): a cross-sectional study linked with routine data. Open Heart, 6(2), e001147
https://doi.org/10.1136/openhrt-2019-001147, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52438
Wannamethee, S., Welsh, P., Papacosta, O., Ellins, E., Halcox, J., Whincup, P., Sattar, N., & Ellins, L. (2017). Circulating soluble receptor for advanced glycation end product: Cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, 36-43.
https://doi.org/10.1016/j.atherosclerosis.2017.07.008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34610
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., McCoubrey, S., Halcox, J., Audrey, S., Ellins, E., Brophy, S., & Ellins, L. (2017). Active children through individual vouchers – evaluation (ACTIVE): protocol for a mixed method randomised control trial to increase physical activity levels in teenagers. BMC Public Health, 18(1)
https://doi.org/10.1186/s12889-017-4554-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34629
James, M., Todd, C., Scott, S., Stratton, G., McCoubrey, S., Christian, D., Halcox, J., Audrey, S., Ellins, E., Anderson, S., Copp, I., Brophy, S., & Ellins, L. (2018). Teenage recommendations to improve physical activity for their age group: a qualitative study. BMC Public Health, 18(1)
https://doi.org/10.1186/s12889-018-5274-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43768
Halcox, J. & Ellins, L. (2009). Endothelial Function Predicts Progression of Carotid Intima-Media Thickness. Circulation, 119, 1005-1012.
https://doi.org/10.1161/CIRCULATIONAHA.108.765701, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16042
Halcox, J. & Ellins, L. (2008). Endothelial dysfunction and Cytomegalovirus. Circulation, 117, 2657-2661.
https://doi.org/10.1161/CIRCULATIONAHA.107.718874, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16044
Parsons, T., Sartini, C., Halcox, J., Smith, K., Ash, S., Lennon, L., Wannamethee, S., Lee, I., Whincup, P., Jefferis, B., & Ellins, L. (2016). Objectively measured physical activity and sedentary behaviour and ankle brachial index: Cross-sectional and longitudinal associations in older men. Atherosclerosis, 247, 28-34.
https://doi.org/10.1016/j.atherosclerosis.2016.01.038, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26357
Arrigoni, F., Matarin, M., Thompson, P., Michaelides, M., McClements, M., Redmond, E., Clarke, L., Ellins, E., Mohamed, S., Pavord, I., Klein, N., Hunt, D., Moore, A., Halcox, J., Sisodiya, S., Halcox, J., & Ellins, L. (2011). Extended extraocular phenotype of PROM1 mutation in kindreds with known autosomal dominant macular dystrophy. European Journal of Human Genetics, 19(9), 1018-1018.
https://doi.org/10.1038/ejhg.2011.73, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27287
http://www.scopus.com/inward/record.url?eid=2-s2.0-80051965468&partnerID=MN8TOARS
Ellins, L., Shipley, M., Rees, D., Kemp, A., Deanfield, J., Brunner, E., & Halcox, J. (2019). Associations of depression-anxiety and dyslipidaemia with subclinical carotid arterial disease: Findings from the Whitehall II Study. European Journal of Preventive Cardiology, 204748731987623
https://doi.org/10.1177/2047487319876230, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51539
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., Demmler, J., McCoubrey, S., Halcox, J., Audrey, S., Ellins, E., Irvine, E., Brophy, S., & Ellins, L. (2019). What works best when implementing a physical activity intervention for teenagers? Reflections from the ACTIVE Project: a qualitative study. BMJ Open, 9(5), e025618
https://doi.org/10.1136/bmjopen-2018-025618, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49910
Chiesa, S., Masi, S., Shipley, M., Ellins, L., Fraser, A., Hughes, A., Patel, R., Khir, A., Halcox, J., Singh-Manoux, A., Kivimaki, M., Celermajer, D., & Deanfield, J. (2019). Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study. European Heart Journal, 40(28), 2300-2309.
https://doi.org/10.1093/eurheartj/ehz189, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49207
Zonoozi, S., Ramsay, S., Papacosta, O., Lennon, L., Ellins, E., Halcox, J., Whincup, P., Wannamethee, S., & Ellins, L. (2019). Chronic kidney disease, cardiovascular risk markers and total mortality in older men: cystatin C versus creatinine. Journal of Epidemiology and Community Health, jech-2018-211719
https://doi.org/10.1136/jech-2018-211719, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49096
Cox, S., Ellins, E., Marealle, A., Newton, C., Soka, D., Sasi, P., Tanna, G., Johnson, W., Makani, J., Prentice, A., Halcox, J., Kirkham, F., & Ellins, L. (2018). Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial. The Lancet Haematology, 5(4), 147-160.
https://doi.org/10.1016/S2352-3026(18)30020-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38119
Ellins, E., Smith, K., Lennon, L., Papacosta, O., Wannamethee, S., Whincup, P., Halcox, J., & Ellins, L. (2017). Arterial pathophysiology and comparison of two devices for pulse wave velocity assessment in elderly men: the British regional heart study. Open Heart, 4(2), e000645
https://doi.org/10.1136/openhrt-2017-000645, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37363
Ellins, E., Rees, D., Deanfield, J., Steptoe, A., Halcox, J., & Ellins, L. (2016). Increased fibrinogen responses to psychophysiological stress predict future endothelial dysfunction implications for cardiovascular disease?. Brain, Behavior, and Immunity
https://doi.org/10.1016/j.bbi.2016.10.017, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30814
Parsons, T., Sartini, C., Ellins, E., Halcox, J., Smith, K., Ash, S., Lennon, L., Wannamethee, S., Lee, I., Whincup, P., Jefferis, B., & Ellins, L. (2016). Objectively measured physical activity, sedentary time and subclinical vascular disease: Cross-sectional study in older British men. Preventive Medicine, 89, 194-199.
https://doi.org/10.1016/j.ypmed.2016.05.031, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28816
Zonoozi, S., Ramsay, S., Papacosta, O., Lennon, L., Ellins, E., Halcox, J., Whincup, P., Goya Wannamethee, S., & Ellins, L. (2017). Self-reported sleep duration and napping, cardiac risk factors and markers of subclinical vascular disease: cross-sectional study in older men. BMJ Open, 7(6), e016396
https://doi.org/10.1136/bmjopen-2017-016396, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34045
Ellins, E., New, K., Datta, D., Watkins, S., Haralambos, K., Rees, A., Rees, D., Halcox, J., Halcox, J., & Ellins, L. (2016). Validation of a new method for non-invasive assessment of vasomotor function. European Journal of Preventive Cardiology, 23(6), 577-583.
https://doi.org/10.1177/2047487315597210, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26653
Connolly, K., Willis, G., Datta, D., Ellins, E., Ladell, K., Price, D., Guschina, I., Rees, D., James, P., & Ellins, L. (2014). Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. The Journal of Lipid Research, 55(10), 2064-2072.
https://doi.org/10.1194/jlr.M049726, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26641
Ingram, T., Fraser, A., Bleasdale, R., Ellins, E., Margulescu, A., Halcox, J., James, P., & Ellins, L. (2013). Low-Dose Sodium Nitrite Attenuates Myocardial Ischemia and Vascular Ischemia-Reperfusion Injury in Human Models. Journal of the American College of Cardiology, 61(25), 2534-2541.
https://doi.org/10.1016/j.jacc.2013.03.050, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26654
Fabbri-Arrigoni, F., Clarke, L., Wang, G., Charakida, M., Ellins, E., Halliday, N., Brogan, P., Deanfield, J., Halcox, J., Klein, N., & Ellins, L. (2012). Levels of circulating endothelial cells and colony-forming units are influenced by age and dyslipidemia. Pediatric Research, 72(3), 299-304.
https://doi.org/10.1038/pr.2012.76, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26655
Whincup, P., Nightingale, C., Owen, C., Rapala, A., Bhowruth, D., Prescott, M., Ellins, E., Donin, A., Masi, S., Rudnicka, A., Sattar, N., Cook, D., Deanfield, J., & Ellins, L. (2012). Ethnic Differences in Carotid Intima-Media Thickness Between UK Children of Black African-Caribbean and White European Origin. Stroke, 43(7), 1747-1754.
https://doi.org/10.1161/STROKEAHA.111.644955, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26656
Ellins, E., Halcox, J., & Ellins, L. (2011). Where Are We Heading with Noninvasive Clinical Vascular Physiology? Why and How Should We Assess Endothelial Function?. Cardiology Research and Practice, 2011, 1-9.
https://doi.org/10.4061/2011/870132, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26687
Ellins, E., Shamaei-Tousi, A., Steptoe, A., Donald, A., OʼMeagher, S., Halcox, J., Henderson, B., & Ellins, L. (2008). The relationship between carotid stiffness and circulating levels of heat shock protein 60 in middle-aged men and women. Journal of Hypertension, 26(12), 2389-2392.
https://doi.org/10.1097/HJH.0b013e328313918b, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26690
Agrawal, V., Ellins, E., Donald, A., Minhas, S., Halcox, J., Ralph, D., & Ellins, L. (2008). ORIGINAL RESEARCH—PEYRONIE'S DISEASE: Systemic Vascular Endothelial Dysfunction in Peyronie's Disease. The Journal of Sexual Medicine, 5(11), 2688-2693.
https://doi.org/10.1111/j.1743-6109.2008.00947.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26691
Ellins, E., Halcox, J., Donald, A., Field, B., Brydon, L., Deanfield, J., Steptoe, A., & Ellins, L. (2008). Arterial stiffness and inflammatory response to psychophysiological stress. Brain, Behavior, and Immunity, 22(6), 941-948.
https://doi.org/10.1016/j.bbi.2008.01.009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26693
Shroff, R., Donald, A., Hiorns, M., Watson, A., Feather, S., Milford, D., Ellins, E., Storry, C., Ridout, D., Deanfield, J., Rees, L., & Ellins, L. (2007). Mineral Metabolism and Vascular Damage in Children on Dialysis. Journal of the American Society of Nephrology, 18(11), 2996-3003.
https://doi.org/10.1681/ASN.2006121397, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26694
Ellins, L., Summers, R., Akbari, A., Lloyd, K., Osborn, D., John, A., Gravenor, M., & Halcox, J. (2024). Blood pressure assessment, treatment and control for primary prevention of cardiovascular disease in patients with and without depression. In European Journal of Preventive CardiologyOxford University Press (OUP).
https://doi.org/10.1093/eurjpc/zwae175.341, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66746

All Research

Journal Articles

Ellins, L., Wareham, K., Harris, D., Hanney, M., Akbari, A., Gilmore, M., Barry, J., Phillips, C., Gravenor, M., & Halcox, J. (2023). Incident atrial fibrillation and adverse clinical outcomes during extended follow-up of participants recruited to the remote heart rhythm sampling using the AliveCor heart monitor to screen for atrial fibrillation: the REHEARSE-AF study. European Heart Journal Open, 3(3)
https://doi.org/10.1093/ehjopen/oead047, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63344
http://dx.doi.org/10.1093/ehjopen/oead047
McKechnie, D., Patel, M., Papacosta, A., Lennon, L., Ellins, L., Halcox, J., Ramsay, S., Whincup, P., & Wannamethee, S. (2022). Associations between inflammation, coagulation, cardiac strain and injury, and subclinical vascular disease with frailty in older men: a cross-sectional study. BMC Geriatrics, 22(1)
https://doi.org/10.1186/s12877-022-03106-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59916
Ellins, L., Harris, D., Lacey, A., Akbari, A., Torabi, F., Smith, D., Jenkins, G., Obaid, D., Chase, A., John, A., Gravenor, M., & Halcox, J. (2022). Achievement of European Society of Cardiology/European Atherosclerosis Society lipid targets in very high-risk patients: Influence of depression and sex. PLOS ONE, 17(2), e0264529
https://doi.org/10.1371/journal.pone.0264529, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59420
McKechnie, D., Papacosta, A., Lennon, L., Ellins, L., Halcox, J., Ramsay, S., Whincup, P., & Wannamethee, S. (2021). Subclinical cardiovascular disease and risk of incident frailty: The British Regional Heart Study. Experimental Gerontology, 154, 111522
https://doi.org/10.1016/j.exger.2021.111522, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57624
Murray, R., Kitaba, N., Antoun, E., Titcombe, P., Barton, S., Cooper, C., Inskip, H., Burdge, G., Mahon, P., Deanfield, J., Halcox, J., Ellins, L., Bryant, J., Peebles, C., Lillycrop, K., Godfrey, K., Hanson, M., & Consortium), . (2021). Influence of Maternal Lifestyle and Diet on Perinatal DNA Methylation Signatures Associated With Childhood Arterial Stiffness at 8 to 9 Years. Hypertension, 78(3), 787-800.
https://doi.org/10.1161/hypertensionaha.121.17396, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56995
http://dx.doi.org/10.1161/hypertensionaha.121.17396
McNarry, M., Lester, L., Ellins, L., Halcox, J., Davies, G., Winn, C., & Mackintosh, K. (2021). Asthma and high-intensity interval training have no effect on clustered cardiometabolic risk or arterial stiffness in adolescents. European Journal of Applied Physiology, 121(7), 1967-1978.
https://doi.org/10.1007/s00421-020-04590-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56651
Davies, R., Williams, J., Sime, K., Jin, H., Thompson, C., Jordan, L., Lang, D., Halcox, J., Ellins, E., Jones, G., Jones, S., Rose-John, S., Williams, A., Choy, E., Halcox, J., & Ellins, L. (2021). The role of interleukin-6 trans-signalling on cardiovascular dysfunction in inflammatory arthritis. Rheumatology, 60(6), 2852-2861.
https://doi.org/10.1093/rheumatology/keaa725, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55470
Ellins, L., Watkins, S., Rees, D., Datta, D., & Halcox, J. (2021). Acute effect of a single session of lipoprotein apheresis on central haemodynamics in patients with familial hypercholesterolaemia. Atherosclerosis, 325, 121-123.
https://doi.org/10.1016/j.atherosclerosis.2021.03.023, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56504
http://dx.doi.org/10.1016/j.atherosclerosis.2021.03.023
Marshall, Z., Mackintosh, K., Lewis, M., Ellins, L., & McNarry, M. (2021). Association of physical activity metrics with indicators of cardiovascular function and control in children with and without type 1 diabetes. Pediatric Diabetes, 22(2), 320-328.
https://doi.org/10.1111/pedi.13159, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55673
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., Demmler, J., McCoubrey, S., Halcox, J., Audrey, S., Ellins, L., & Brophy, S. (2020). Active Children Through Individual Vouchers Evaluation: A Mixed-Method RCT. American Journal of Preventive Medicine, 58(2), 232-243.
https://doi.org/10.1016/j.amepre.2019.10.005, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52367
Zonoozi, S., Ramsay, S., Papacosta, O., Lennon, L., Ellins, E., Halcox, J., Whincup, P., Wannamethee, S., & Ellins, L. (2019). Chronic kidney disease, cardiovascular risk markers and total mortality in older men: cystatin C versus creatinine. Journal of Epidemiology and Community Health, jech-2018-211719
https://doi.org/10.1136/jech-2018-211719, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49096
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., Demmler, J., McCoubrey, S., Halcox, J., Audrey, S., Ellins, L., & Brophy, S. (2019). Predictors of cardiovascular health in teenagers (aged 13–14 years): a cross-sectional study linked with routine data. Open Heart, 6(2), e001147
https://doi.org/10.1136/openhrt-2019-001147, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52438
Ellins, L., Shipley, M., Rees, D., Kemp, A., Deanfield, J., Brunner, E., & Halcox, J. (2019). Associations of depression-anxiety and dyslipidaemia with subclinical carotid arterial disease: Findings from the Whitehall II Study. European Journal of Preventive Cardiology, 204748731987623
https://doi.org/10.1177/2047487319876230, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51539
Chiesa, S., Masi, S., Shipley, M., Ellins, L., Fraser, A., Hughes, A., Patel, R., Khir, A., Halcox, J., Singh-Manoux, A., Kivimaki, M., Celermajer, D., & Deanfield, J. (2019). Carotid artery wave intensity in mid- to late-life predicts cognitive decline: the Whitehall II study. European Heart Journal, 40(28), 2300-2309.
https://doi.org/10.1093/eurheartj/ehz189, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49207
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., Demmler, J., McCoubrey, S., Halcox, J., Audrey, S., Ellins, E., Irvine, E., Brophy, S., & Ellins, L. (2019). What works best when implementing a physical activity intervention for teenagers? Reflections from the ACTIVE Project: a qualitative study. BMJ Open, 9(5), e025618
https://doi.org/10.1136/bmjopen-2018-025618, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa49910
James, M., Todd, C., Scott, S., Stratton, G., McCoubrey, S., Christian, D., Halcox, J., Audrey, S., Ellins, E., Anderson, S., Copp, I., Brophy, S., & Ellins, L. (2018). Teenage recommendations to improve physical activity for their age group: a qualitative study. BMC Public Health, 18(1)
https://doi.org/10.1186/s12889-018-5274-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43768
Cox, S., Ellins, E., Marealle, A., Newton, C., Soka, D., Sasi, P., Tanna, G., Johnson, W., Makani, J., Prentice, A., Halcox, J., Kirkham, F., & Ellins, L. (2018). Ready-to-use food supplement, with or without arginine and citrulline, with daily chloroquine in Tanzanian children with sickle-cell disease: a double-blind, random order crossover trial. The Lancet Haematology, 5(4), 147-160.
https://doi.org/10.1016/S2352-3026(18)30020-6, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa38119
Ellins, E., Smith, K., Lennon, L., Papacosta, O., Wannamethee, S., Whincup, P., Halcox, J., & Ellins, L. (2017). Arterial pathophysiology and comparison of two devices for pulse wave velocity assessment in elderly men: the British regional heart study. Open Heart, 4(2), e000645
https://doi.org/10.1136/openhrt-2017-000645, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa37363
Wannamethee, S., Welsh, P., Papacosta, O., Ellins, E., Halcox, J., Whincup, P., Sattar, N., & Ellins, L. (2017). Circulating soluble receptor for advanced glycation end product: Cross-sectional associations with cardiac markers and subclinical vascular disease in older men with and without diabetes. Atherosclerosis, 264, 36-43.
https://doi.org/10.1016/j.atherosclerosis.2017.07.008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34610
James, M., Christian, D., Scott, S., Todd, C., Stratton, G., McCoubrey, S., Halcox, J., Audrey, S., Ellins, E., Brophy, S., & Ellins, L. (2017). Active children through individual vouchers – evaluation (ACTIVE): protocol for a mixed method randomised control trial to increase physical activity levels in teenagers. BMC Public Health, 18(1)
https://doi.org/10.1186/s12889-017-4554-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34629
Zonoozi, S., Ramsay, S., Papacosta, O., Lennon, L., Ellins, E., Halcox, J., Whincup, P., Goya Wannamethee, S., & Ellins, L. (2017). Self-reported sleep duration and napping, cardiac risk factors and markers of subclinical vascular disease: cross-sectional study in older men. BMJ Open, 7(6), e016396
https://doi.org/10.1136/bmjopen-2017-016396, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa34045
Ellins, E., Rees, D., Deanfield, J., Steptoe, A., Halcox, J., & Ellins, L. (2016). Increased fibrinogen responses to psychophysiological stress predict future endothelial dysfunction implications for cardiovascular disease?. Brain, Behavior, and Immunity
https://doi.org/10.1016/j.bbi.2016.10.017, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30814
Parsons, T., Sartini, C., Ellins, E., Halcox, J., Smith, K., Ash, S., Lennon, L., Wannamethee, S., Lee, I., Whincup, P., Jefferis, B., & Ellins, L. (2016). Objectively measured physical activity, sedentary time and subclinical vascular disease: Cross-sectional study in older British men. Preventive Medicine, 89, 194-199.
https://doi.org/10.1016/j.ypmed.2016.05.031, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28816
Ellins, E., New, K., Datta, D., Watkins, S., Haralambos, K., Rees, A., Rees, D., Halcox, J., Halcox, J., & Ellins, L. (2016). Validation of a new method for non-invasive assessment of vasomotor function. European Journal of Preventive Cardiology, 23(6), 577-583.
https://doi.org/10.1177/2047487315597210, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26653
Parsons, T., Sartini, C., Halcox, J., Smith, K., Ash, S., Lennon, L., Wannamethee, S., Lee, I., Whincup, P., Jefferis, B., & Ellins, L. (2016). Objectively measured physical activity and sedentary behaviour and ankle brachial index: Cross-sectional and longitudinal associations in older men. Atherosclerosis, 247, 28-34.
https://doi.org/10.1016/j.atherosclerosis.2016.01.038, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26357
Connolly, K., Willis, G., Datta, D., Ellins, E., Ladell, K., Price, D., Guschina, I., Rees, D., James, P., & Ellins, L. (2014). Lipoprotein-apheresis reduces circulating microparticles in individuals with familial hypercholesterolemia. The Journal of Lipid Research, 55(10), 2064-2072.
https://doi.org/10.1194/jlr.M049726, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26641
Ingram, T., Fraser, A., Bleasdale, R., Ellins, E., Margulescu, A., Halcox, J., James, P., & Ellins, L. (2013). Low-Dose Sodium Nitrite Attenuates Myocardial Ischemia and Vascular Ischemia-Reperfusion Injury in Human Models. Journal of the American College of Cardiology, 61(25), 2534-2541.
https://doi.org/10.1016/j.jacc.2013.03.050, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26654
Fabbri-Arrigoni, F., Clarke, L., Wang, G., Charakida, M., Ellins, E., Halliday, N., Brogan, P., Deanfield, J., Halcox, J., Klein, N., & Ellins, L. (2012). Levels of circulating endothelial cells and colony-forming units are influenced by age and dyslipidemia. Pediatric Research, 72(3), 299-304.
https://doi.org/10.1038/pr.2012.76, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26655
Whincup, P., Nightingale, C., Owen, C., Rapala, A., Bhowruth, D., Prescott, M., Ellins, E., Donin, A., Masi, S., Rudnicka, A., Sattar, N., Cook, D., Deanfield, J., & Ellins, L. (2012). Ethnic Differences in Carotid Intima-Media Thickness Between UK Children of Black African-Caribbean and White European Origin. Stroke, 43(7), 1747-1754.
https://doi.org/10.1161/STROKEAHA.111.644955, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26656
Arrigoni, F., Matarin, M., Thompson, P., Michaelides, M., McClements, M., Redmond, E., Clarke, L., Ellins, E., Mohamed, S., Pavord, I., Klein, N., Hunt, D., Moore, A., Halcox, J., Sisodiya, S., Halcox, J., & Ellins, L. (2011). Extended extraocular phenotype of PROM1 mutation in kindreds with known autosomal dominant macular dystrophy. European Journal of Human Genetics, 19(9), 1018-1018.
https://doi.org/10.1038/ejhg.2011.73, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27287
http://www.scopus.com/inward/record.url?eid=2-s2.0-80051965468&partnerID=MN8TOARS
Ellins, E., Halcox, J., & Ellins, L. (2011). Where Are We Heading with Noninvasive Clinical Vascular Physiology? Why and How Should We Assess Endothelial Function?. Cardiology Research and Practice, 2011, 1-9.
https://doi.org/10.4061/2011/870132, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26687
Halcox, J. & Ellins, L. (2009). Endothelial Function Predicts Progression of Carotid Intima-Media Thickness. Circulation, 119, 1005-1012.
https://doi.org/10.1161/CIRCULATIONAHA.108.765701, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16042
Ellins, E., Shamaei-Tousi, A., Steptoe, A., Donald, A., OʼMeagher, S., Halcox, J., Henderson, B., & Ellins, L. (2008). The relationship between carotid stiffness and circulating levels of heat shock protein 60 in middle-aged men and women. Journal of Hypertension, 26(12), 2389-2392.
https://doi.org/10.1097/HJH.0b013e328313918b, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26690
Agrawal, V., Ellins, E., Donald, A., Minhas, S., Halcox, J., Ralph, D., & Ellins, L. (2008). ORIGINAL RESEARCH—PEYRONIE'S DISEASE: Systemic Vascular Endothelial Dysfunction in Peyronie's Disease. The Journal of Sexual Medicine, 5(11), 2688-2693.
https://doi.org/10.1111/j.1743-6109.2008.00947.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26691
Ellins, E., Halcox, J., Donald, A., Field, B., Brydon, L., Deanfield, J., Steptoe, A., & Ellins, L. (2008). Arterial stiffness and inflammatory response to psychophysiological stress. Brain, Behavior, and Immunity, 22(6), 941-948.
https://doi.org/10.1016/j.bbi.2008.01.009, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26693
Halcox, J. & Ellins, L. (2008). Endothelial dysfunction and Cytomegalovirus. Circulation, 117, 2657-2661.
https://doi.org/10.1161/CIRCULATIONAHA.107.718874, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa16044
Shroff, R., Donald, A., Hiorns, M., Watson, A., Feather, S., Milford, D., Ellins, E., Storry, C., Ridout, D., Deanfield, J., Rees, L., & Ellins, L. (2007). Mineral Metabolism and Vascular Damage in Children on Dialysis. Journal of the American Society of Nephrology, 18(11), 2996-3003.
https://doi.org/10.1681/ASN.2006121397, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26694

Conference Contributions

Ellins, L., Summers, R., Akbari, A., Lloyd, K., Osborn, D., John, A., Gravenor, M., & Halcox, J. (2024). Blood pressure assessment, treatment and control for primary prevention of cardiovascular disease in patients with and without depression. In European Journal of Preventive CardiologyOxford University Press (OUP).
https://doi.org/10.1093/eurjpc/zwae175.341, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66746

Taught Modules

PM-266 The Cardiovascular System

Leading on from the first year Human Physiology Module (PM-154), the Cardiovascular Module will introduce and define the fundamental cellular mechanisms that regulate the physiology of healthy cardiovascular function. The Module will describe the processes that allow regular heartbeat and blood vessel function and how perturbations in the systems covered may lead to pathophysiological conditions. There will be an emphasis on experimental approaches used to study the cardiovascular mechanisms described.
PM-266C Y System Gardiofasgwlaidd

Gan adeiladu ar fodiwl Ffisioleg Ddynol y flwyddyn gyntaf (PM-154), bydd y Modiwl Cardiofasgwlaidd yn cyflwyno ac yn diffinio'r mecanweithiau cellol sylfaenol sy'n rheoleiddio ffisioleg gweithrediad cardiofasgiwlaidd iach. Bydd y modiwl yn disgrifio'r prosesau sy'n galluogi gweithrediad iach curiad y galon a'r pibellau gwaed a sut gall aflonyddiadau yn y systemau a drafodir arwain at gyflyrau pathoffisiolegol. Bydd pwyslais ar ddulliau arbrofol a ddefnyddir i astudio'r mecanweithiau cardiofasgwlaidd a ddisgrifir.
PM-344 Capstone Project

The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.