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Professor Lisa Wallace

Professor

Biomedical Sciences

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Available For Postgraduate Supervision

Research Links

https://orcid.org/0000-0001-7471-9833

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About

Lisa earned a BSc in Biology and a PhD in Pharmacology and Toxicology from Virginia Commonwealth University, Medical College of Virginia in the United States. After a fellowship at the University of California, San Francisco studying the basic science of addiction, she was appointed to a lectureship in Medical Pharmacology at Cardiff University. She is now a Professor of Pharmacology and Medical Sciences Education here at Swansea University where she is the Associate Dean (International) for the Faculty of Medicine, Health and Life Science, and Chair of the University’s Programme Approval Committee. She is a Principal Fellow of the Higher Education Academy with interests in curriculum development and quality assurance, having worked on projects with the British Pharmacological Society, the Royal Society of Biology, the Quality Assurance Agency, and the Norwegian Agency for Quality Assurance in Education. Her laboratory work focuses on novel in vivo, invertebrate models for the investigation of psychoactive substances. Lisa is a Fellow of the Royal Society of Biology, and a Fellow of the British Pharmacological Society. She is a former British Pharmacological Society Vice President for Academic Development and currently serves as a General Trustee.

Areas Of Expertise

Behavioural pharmacology
Pharmacology
Drugs of abuse
Neuroscience
Quality assurance in higher education
Curriculum development

Career Highlights

Teaching Interests

Pharmacology
Neuroscience
Scientific writing

Research Award Highlights

Publications

Research Highlights

Seeley, A., Bellamy, C., Davies, N., & Wallace, L. (2021). Lumbriculus variegatus: A novel organism for in vivo pharmacology education. Pharmacology Research & Perspectives, 9(5)
https://doi.org/10.1002/prp2.853, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57739
Wallace, L., Zecharia, A., Guilding, C., Tucker, S., & McFadzean, I. (2021). Developing a new undergraduate pharmacology core curriculum: The British Pharmacological Society Delphi Method. Pharmacology Research & Perspectives, 9(4)
https://doi.org/10.1002/prp2.832, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57548
John-Matthews, J., Wallace, M., Robinson, L., & Wallace, L. (2017). The Delphi technique in radiography education research. Radiography
https://doi.org/10.1016/j.radi.2017.03.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32930
Wallace, L. & Newton, P. (2014). Turnaround time and market capacity in contract cheating. Educational Studies, 40(2), 233-236.
https://doi.org/10.1080/03055698.2014.889597, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa17023
Newton, P., Wallace, M., McKimm, J., & Wallace, L. (2012). Improved quality and quantity of written feedback is associated with a structured feedback proforma. Journal of Educational Evaluation for Health Professions, 9(10), online-online.
https://doi.org/10.3352/jeehp.2012.9.10, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12687
http://www.jeehp.org/DOIx.php?id=10.3352/jeehp.2012.9.10
Wallace, M., Newton, P., Newton, P., & Wallace, L. (2012). eLS. John Wiley & Sons Ltd
https://doi.org/10.1002/9780470015902.a0002010.pub3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12686
http://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0002010.pub3/abstract
Wallace, M., Newton, P., McMahon, T., Connolly, J., Huibers, A., Whistler, J., Messing, R., Newton, P., & Wallace, L. (2009). PKCɛ Regulates Behavioral Sensitivity, Binding and Tolerance to the CB1 Receptor Agonist WIN55,212-2. Neuropsychopharmacology, 34(7), 1733-1742.
https://doi.org/10.1038/npp.2008.230, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10649
Lesscher, H., Wallace, M., Zeng, L., Wang, V., Deitchman, J., McMahon, T., Messing, R., Newton, P., Newton, P., & Wallace, L. (2009). Amygdala protein kinase C epsilon controls alcohol consumption. Genes, Brain and Behavior, 8(5), 493-499.
https://doi.org/10.1111/j.1601-183X.2009.00485.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10359
Newton, P., Zeng, L., Wang, V., Connolly, J., Wallace, M., Kim, C., Shin, H., Belardetti, F., Snutch, T., Messing, R., Newton, P., & Wallace, L. (2008). A Blocker of N- and T-type Voltage-Gated Calcium Channels Attenuates Ethanol-Induced Intoxication, Place Preference, Self-Administration, and Reinstatement. Journal of Neuroscience, 28(45), 11712-11719.
https://doi.org/10.1523/JNEUROSCI.3621-08.2008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10648
Wallace, M., Newton, P., Oyasu, M., McMahon, T., Chou, W., Connolly, J., Messing, R., Newton, P., & Wallace, L. (2007). Acute Functional Tolerance to Ethanol Mediated by Protein Kinase Cɛ. Neuropsychopharmacology, 32(1), 127-136.
https://doi.org/10.1038/sj.npp.1301059, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10962

All Research

Journal Articles

Seeley, A., MAHMOOD, R., BELLAMY, C., ROOME, E., WILLIAMS, B., Davies, N., & Wallace, L. (2024). Concentration- and time-dependent behavioural effects of ethanol on Lumbriculus variegatus. Genes, Brain and Behavior, 23(5), e70006
https://doi.org/10.1111/gbb.70006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa68104
Carriere, J., Davies, N., Cunningham, M., Wallace, L., & Seeley, A. (2023). Co-created in vivo pharmacology practical classes using the novel organism Lumbriculus variegatus. Pharmacology Research and Perspectives, 11(6)
https://doi.org/10.1002/prp2.1158, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63445
Seeley, A., Bellamy, C., Davies, N., & Wallace, L. (2021). Lumbriculus variegatus: A novel organism for in vivo pharmacology education. Pharmacology Research & Perspectives, 9(5)
https://doi.org/10.1002/prp2.853, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57739
Wallace, L., Zecharia, A., Guilding, C., Tucker, S., & McFadzean, I. (2021). Developing a new undergraduate pharmacology core curriculum: The British Pharmacological Society Delphi Method. Pharmacology Research & Perspectives, 9(4)
https://doi.org/10.1002/prp2.832, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57548
John-Matthews, J., Wallace, M., Robinson, L., & Wallace, L. (2017). The Delphi technique in radiography education research. Radiography
https://doi.org/10.1016/j.radi.2017.03.007, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa32930
Wallace, L. & Newton, P. (2014). Turnaround time and market capacity in contract cheating. Educational Studies, 40(2), 233-236.
https://doi.org/10.1080/03055698.2014.889597, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa17023
Newton, P., Wallace, M., McKimm, J., & Wallace, L. (2012). Improved quality and quantity of written feedback is associated with a structured feedback proforma. Journal of Educational Evaluation for Health Professions, 9(10), online-online.
https://doi.org/10.3352/jeehp.2012.9.10, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12687
http://www.jeehp.org/DOIx.php?id=10.3352/jeehp.2012.9.10
Wallace, M., Newton, P., McMahon, T., Connolly, J., Huibers, A., Whistler, J., Messing, R., Newton, P., & Wallace, L. (2009). PKCɛ Regulates Behavioral Sensitivity, Binding and Tolerance to the CB1 Receptor Agonist WIN55,212-2. Neuropsychopharmacology, 34(7), 1733-1742.
https://doi.org/10.1038/npp.2008.230, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10649
Lesscher, H., Wallace, M., Zeng, L., Wang, V., Deitchman, J., McMahon, T., Messing, R., Newton, P., Newton, P., & Wallace, L. (2009). Amygdala protein kinase C epsilon controls alcohol consumption. Genes, Brain and Behavior, 8(5), 493-499.
https://doi.org/10.1111/j.1601-183X.2009.00485.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10359
Newton, P., Zeng, L., Wang, V., Connolly, J., Wallace, M., Kim, C., Shin, H., Belardetti, F., Snutch, T., Messing, R., Newton, P., & Wallace, L. (2008). A Blocker of N- and T-type Voltage-Gated Calcium Channels Attenuates Ethanol-Induced Intoxication, Place Preference, Self-Administration, and Reinstatement. Journal of Neuroscience, 28(45), 11712-11719.
https://doi.org/10.1523/JNEUROSCI.3621-08.2008, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10648
Wallace, M., Newton, P., Oyasu, M., McMahon, T., Chou, W., Connolly, J., Messing, R., Newton, P., & Wallace, L. (2007). Acute Functional Tolerance to Ethanol Mediated by Protein Kinase Cɛ. Neuropsychopharmacology, 32(1), 127-136.
https://doi.org/10.1038/sj.npp.1301059, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10962
Newton, P., Kim, J., McGeehan, A., Paredes, J., Chu, K., Wallace, M., Roberts, A., Hodge, C., Messing, R., Newton, P., & Wallace, L. (2007). Increased response to morphine in mice lacking protein kinase C epsilon. Genes, Brain and Behavior, 6(4), 329-338.
https://doi.org/10.1111/j.1601-183X.2006.00261.x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10961
Z.-H, Q., Song, M., Wallace, M., Wang, D., Newton, P., McMahon, T., Chou, W., Zhang, C., Shokat, K., Messing, R., Newton, P., & Wallace, L. (2007). Protein Kinase C Regulates -Aminobutyrate Type A Receptor Sensitivity to Ethanol and Benzodiazepines through Phosphorylation of 2 Subunits. Journal of Biological Chemistry, 282(45), 33052-33063.
https://doi.org/10.1074/jbc.M707233200, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10958
Newton, P., Newton, P., & Wallace, L. (2004). Deletion of N-Type Calcium Channels Alters Ethanol Reward and Reduces Ethanol Consumption in Mice. Journal of Neuroscience, 24(44), 9862-9869.
https://doi.org/10.1523/JNEUROSCI.3446-04.2004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10966
Wallace, M. & Wallace, L. (2003). The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy. Journal of Pharmacology and Experimental Therapeutics, 307(1), 129-137.
https://doi.org/10.1124/jpet.103.051920, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31947
Wallace, M., Martin, B., DeLorenzo, R., & Wallace, L. (2002). Evidence for a physiological role of endocannabinoids in the modulation of seizure threshold and severity. European Journal of Pharmacology, 452(3), 295-301.
https://doi.org/10.1016/S0014-2999(02)02331-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31948
Wallace, M., Wiley, J., Martin, B., DeLorenzo, R., & Wallace, L. (2001). Assessment of the role of CB1 receptors in cannabinoid anticonvulsant effects. European Journal of Pharmacology, 428(1), 51-57.
https://doi.org/10.1016/S0014-2999(01)01243-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31949
Robinson, S. & Wallace, L. (1997). Perinatal Methadone Exposure Affects Dopamine, Norepinephrine, and Serotonin in the Weanling Rat. Neurotoxicology and Teratology, 19(4), 295-303.
https://doi.org/10.1016/S0892-0362(97)00018-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31956
Robinson, S., Kunko, P., Smith, J., Wallace, M., Mo, Q., Maher, J., & Wallace, L. (1997). Extracellular aspartate concentration increases in nucleus accumbens after cocaine sensitization. European Journal of Pharmacology, 319(1), 31-36.
https://doi.org/10.1016/S0014-2999(96)00923-5, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31957
Kunko, P., Wallace, M., Robinson, S., & Wallace, L. (1996). Gestational cocaine and ethanol exposure alter spontaneous and cocaine-induced behavior in weanling rats. Pharmacology Biochemistry and Behavior, 55(4), 559-564.
https://doi.org/10.1016/S0091-3057(96)00283-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31959
Robinson, S., Mo, Q., Maher, J., Wallace, M., Kunko, P., & Wallace, L. (1996). Perinatal exposure to methadone affects central cholinergic activity in the weanling rat. Drug and Alcohol Dependence, 41(2), 119-126.
https://doi.org/10.1016/0376-8716(96)01238-0, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa31960

Book Chapters

Wallace, M., Newton, P., Newton, P., & Wallace, L. (2012). eLS. John Wiley & Sons Ltd
https://doi.org/10.1002/9780470015902.a0002010.pub3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12686
http://onlinelibrary.wiley.com/doi/10.1002/9780470015902.a0002010.pub3/abstract

Supervision

Investigating the response of Lumbriculus variegatus to cannabidiol and endocannabinoids (current)

MSc

Other supervisor: Dr Aidan Seeley
To observe the effects of environmentally relevant concentrations of CBD and CBD-related compounds using the invertebrate model Lumbriculus variegatus. (current)

MSc

Other supervisor: Dr Nia Davies
Lumbriculus Variegatus: Investigating a Novel in vivo Model for Substances of Abuse. (awarded 2024)

MSc

Other supervisor: Dr Nia Davies
Lumbriculus variegatus: A novel organism for in vivo pharmacology research (awarded 2023)

MSc

Other supervisor: Dr Nia Davies

Taught Modules

PM-147 Introduction to Toxicology: The Dose Makes the Poison

We are surrounded by substances that may do our bodies harm i.e. poisons. The harm these poisons causes depends on our exposure - the dose. The science of toxicology, a discipline that crosscuts biology, chemistry, pharmacology, and medicine, is based on the principle that the dose makes the poison. This module will provide you with an introduction to toxicology and how dose-response relationships relate to the physiological effects of toxic substances. You will explore how they produce cellular and chemical changes that cause tissues and organs to malfunction. You will learn how the structure and function of these tissues can be affected to varying degrees and begin to understand how tissue may repair itself and when the damage is reversible, permanent or fatal. You will also learn how we use toxic substances to our advantage in both the laboratory and within the clinic.
PM-261 Pharmacology: Dynamics and Kinetics

Pharmacology is the science of how drugs act on the body and how the body acts on drugs. Pharmacology investigates the chemical and physical properties of drugs, how those properties confer actions on living tissues and how those actions affect health and disease. In this module, students will examine how the body interacts with drugs (pharmacokinetics) and how the drug interacts with the body (pharmacodynamics). Students will learn how the body absorbs, distributed, metabolizes and excretes drugs as well as complex nature of how drugs produce their beneficial, or harmful, effects in living organisms.
PM-344 Capstone Project

The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.

Professor Lisa Wallace

Email address

LinkedIn Account

Research Links

About

Areas Of Expertise

Career Highlights

Publications

Research Highlights

All Research

Journal Articles

Book Chapters

Supervision

Investigating the response of Lumbriculus variegatus to cannabidiol and endocannabinoids (current)

To observe the effects of environmentally relevant concentrations of CBD and CBD-related compounds using the invertebrate model Lumbriculus variegatus. (current)

Lumbriculus Variegatus: Investigating a Novel in vivo Model for Substances of Abuse. (awarded 2024)

Lumbriculus variegatus: A novel organism for in vivo pharmacology research (awarded 2023)

Taught Modules

PM-147 Introduction to Toxicology: The Dose Makes the Poison

PM-261 Pharmacology: Dynamics and Kinetics

PM-344 Capstone Project