Siân-Eleri obtained a BSc (Hons) in Biomedical Science from University of Wales Institute Cardiff. She was awarded a PhD from the School of Pharmacy and Pharmaceutical Sciences, Cardiff University for the investigation of myosin light chain-dependent modulation of tight junction function through the actions of membrane-permeant peptides.
Siân-Eleri has a keen interest in studying ways to increase the intrinsic protection of tissues against pathogens.
Siân-Eleri lectures through the medium of Welsh and English on subjects such as cell biology and laboratory skills.
Siân-Eleri’s research is focused on cellular resilience to bacterial pore-forming toxins. The ability to tolerate pathogenic bacteria largely depends on the resilience of the host’s tissue cells to damage caused by bacterial virulence factors. Therefore, studying ways to improve the intrinsic protection of tissues against pathogens is highly beneficial because “prevention is better than cure”.
This module aims to give students a broad overview of the structure and function of components of the human body, from cells and their organisation to the function of specialised cells in various organs. The role of the specialised cells will be explored using blood as an example. Students will also obtain an appreciation of the cancer cell proliferation and the various causes of leukaemias.
This module will provide students with a broad introduction to fundamental concepts in Eukaryotic cell biology, such as investigating the origins of the cell, the structure or eukaryotic cells, the different types of specialised cells, and cells which help prevent disease. There will be a general focus on human cells throughout the module with some references to other organisms when needed. Students will gain practical experience in identification and differentiation of cells from different human and animal species.
Bydd y modiwl hwn yn darparu cyflwyniad bras i gysyniadau sylfaenol ym maes bioleg celloedd Ewcaryotig, gan ymchwilio i darddiad y gell, strwythur y gell a chelloedd arbenigol a chelloedd mewn clefyd. Bydd ffocws cyffredinol ar gelloedd dynol drwy gydol y modiwl, gan gyfeirio at organebau eraill yn ôl yr angen. Bydd myfyrwyr yn cael profiad ymarferol o nodi celloedd, gwahaniaethu rhwng gwahanol gelloedd dynol a rhywogaethau o anifeiliaid.
The aim of this module is to provide students with an initial experience of what it is to be a modern medical scientist, from the initial experimental planning, to performing experiments within the laboratory with data acquisition and analysis and finally to the communication of scientific findings to a wider audience. Students will develop basic skill sets in the four most important research skill areas of practical laboratory skills, data analysis, collaboration and communication. The module will be both theoretical and applied, where the student will be instructed in methods essential for data acquisition and data analyses but will also actively participate in the laboratory, using broadly applicable experimental techniques. In addition, students will learn about health and safety within a laboratory environment and the current ethics regulations surrounding the use of humans, human tissue and animals within medical research. Furthermore, students will develop their communication skill sets not only through essay writing but also will develop their oral presentation skill set and their collaboration skills through a group presentation and tutorial classes.
Nod y modiwl hwn yw darparu¿r sgiliau sylfaenol sydd eu hangen ar fyfyrwyr ar gyfer ymchwil labordy ym maes y gwyddorau meddygol cymhwysol. Bydd y modiwl yn cynnwys gwaith damcaniaethol a chymhwysol: caiff y myfyriwr ei hyfforddi mewn dulliau sy¿n hanfodol ar gyfer caffael data a¿i ddadansoddi, ond bydd hefyd yn cymryd rhan weithredol yn y labordy, gan ddefnyddio¿n fras y technegau arbrofol perthnasol. Byddant hefyd yn datblygu sgiliau nad ydynt yn dechnegau arbrofol yn eu hunain, ond sydd er hynny, yn sylfaenol i¿r broses wyddonol, megis, 'mathemateg y labordy¿, cyrchu gwybodaeth, cyfeirnodi, moeseg ac iechyd a diogelwch.
Cells are the fundamental units of life, forming the basis of all biological systems. This module provides a comprehensive introduction to cell biology, covering both eukaryotic and prokaryotic cells, their origins, and their evolutionary significance. Students will explore the molecular building blocks of life, gaining insight into how atoms and molecules combine to form essential macromolecules, ultimately giving rise to cells. The module examines the organization and function of eukaryotic cells, focusing on key organelles such as the nucleus (genetic regulation), mitochondria (energy production), cytoskeleton (structural support and transport), endoplasmic reticulum (protein processing), and Golgi apparatus (lipid processing). Students will also explore cell-to-cell communication via ligands and receptors, as well as the mechanisms of controlled cell death (apoptosis). Additionally, the module covers specialized eukaryotic cells, including those of the nervous and immune systems, as well as the role of stem cells in development. Prokaryotic cell biology will be explored in depth, covering the structure, function, and diversity of bacteria and archaea. Topics include cell envelope composition, motility, defense mechanisms, communication strategies, and adaptation to extreme environments. The module will also highlight the significance of prokaryotes in health, disease, and biotechnology. Furthermore, students will examine non-living entities such as viruses and bacteriophages, comparing their unique properties with those of eukaryotic and prokaryotic cells. Through a combination of lectures, laboratory sessions, and workshops, this module will provide students with both theoretical knowledge and practical skills in cell biology, emphasizing its relevance to human health and scientific research.
Celloedd yw unedau sylfaenol bywyd, gan ffurfio sylfaen yr holl systemau biolegol. Mae'r modiwl hwn yn cynnig cyflwyniad cynhwysfawr i fioleg celloedd, gan gynnwys celloedd ewcaryotig a phrocaryotig, eu tarddleoedd, a'u harwyddocâd esblygol. Bydd myfyrwyr yn archwilio seiliau bywyd moleciwlaidd, gan ennill dealltwriaeth o sut mae atomau a moleciwlau yn cyfuno i ffurfio macrofoleciwlau hanfodol, sydd yn y pen draw yn achosi i gelloedd ddatblygu. Mae'r modiwl yn archwilio trefniadaeth a swyddogaeth celloedd ewcaryotig, gan ganolbwyntio ar organynnau allweddol megis y cnewyllyn (rheoleiddio genetig), mitocondria (cynhyrchu egni), cytosgerbwd (cymorth a chludiant strwythurol), reticwlwm endoplasmig (prosesu protein), a'r organigyn Golgi (prosesu lipidau). Bydd myfyrwyr hefyd yn archwilio cyfathrebu rhwng celloedd drwy gyfrwng ligandau a derbynyddion, yn ogystal â dulliau marwolaeth celloedd a reolir (apoptosis). Yn ogystal, mae'r modiwl yn cynnwys celloedd ewcaryotig arbenigol, gan gynnwys rhai y system nerfol a'r system imiwnedd, yn ogystal â rôl bôn-gelloedd sy'n datblygu. Archwilir bioleg celloedd procaryotig mewn manylder, gan drafod strwythur, swyddogaeth, ac amrywiaeth bacteria ac archaea. Mae pynciau'n cynnwys cyfansoddiad cell amlen, symudoldeb, mecanweithiau amddiffyn, strategaethau cyfathrebu, ac addasu i amgylcheddau eithafol. Bydd y modiwl hwn hefyd yn amlygu pwysigrwydd procaryotau mewn iechyd, afiechyd, a biotechnoleg. Ar ben hynny, bydd myfyrwyr yn archwilio endidau anfyw megis firysau a bacterioffagau, gan gymharu eu priodoleddau unigryw â phriodoleddau celloedd ewcaryotig a phrocaryotig. Drwy gyfuniad o ddarlithoedd, sesiynau mewn labordy, a gweithdai, bydd y modiwl hwn yn darparu gwybodaeth ddamcaniaethol a sgiliau ymarferol mewn bioleg celloedd i fyfyrwyr, gan bwysleisio ei berthnasedd i iechyd dynol ac ymchwil wyddonol.
The educational intention of the module is to allow the student to consider the contemporary practice of Medicine within the United Kingdom. This will include understanding the professional regulation, financial constraints and societal and personal challenges, within which medicine and other healthcare activities are practiced.
The aim of this module is to provide a capstone experience to students¿ learning, through participating in their own enquiry-based research project, with guidance from an academic supervisor. The project may be laboratory or non-laboratory based, but it will always involve a research question that is drawn from the literature, and focused on a topic relevant to the life sciences. It will ask a research question and involve the critical analysis of research findings. Students will refine their oral and written communication skills to a graduate level through an oral presentation and dissertation on their research findings and conclusions.
Nod y modiwl hwn yw rhoi cyfle i fyfyrwyr gael profiad dysgu capfaen drwy gymryd rhan yn eu prosiect eu hunain yn seiliedig ar gwestiwn ymchwil. Gall y prosiect fod mewn labordy neu heb fod yn labordy ond bydd bob amser yn cynnwys cwestiwn ymchwil sy'n deillio o'r llenyddiaeth, ac sy'n canolbwyntio ar bwnc perthnasol i wyddor feddygol. Bydd yn gofyn cwestiwn ymchwil newydd ac yn cynnwys dadansoddiad beirniadol o ganfyddiadau ymchwil. Bydd myfyrwyr yn mireinio eu sgiliau cyfathrebu llafar ac ysgrifenedig i lefel raddedig, drwy lunio cyflwyniad rhagarweiniol ar gefndir y prosiect, ynghyd â thraethawd estynedig a chyflwyniad llafar ar ganfyddiadau eu hymchwil.
This module is for students with an interest in teaching, science communication, and medicine. Students will complete an enquiry-based research project, based within the field of pedagogy or science communication, with guidance from an academic supervisor. Projects may be completed in collaboration with local schools/colleges, community groups, science outreach programmes (e.g. Oriel Science), in clinical/patient settings, or within Higher Education. Students will engage with workshops and digital resources to introduce various themes surrounding pedagogy and science communication to prepare them for their research project. Students will be required to critically analyse their research findings and produce a teaching or outreach activity/resource. Students will refine their oral and written communication skills to graduate level through an oral presentation and dissertation.
This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics: ¿ Human Anatomy and Physiology ¿ across the life span ¿ Good laboratory practice and Sustainability ¿ Key principles of cellular pathology, clinical biochemistry, medical microbiology, clinical immunology, clinical genetics and haematology ¿ Quality Management
This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics across the life span: ¿ Human Anatomy, Physiology and Pathology ¿ Pharmacology and Toxicology ¿ Key principles of cell pathology, clinical biochemistry, clinical microbiology, clinical immunology, and clinical genetics ¿ Transfusion Science ¿ Quality Management ¿ Near-patient testing (NPT)/Point of Care Testing
This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics: ¿ Human Anatomy, Physiology and Pathology ¿ Pharmacology and Toxicology ¿ Good laboratory practice and Sustainability ¿ Key principles of clinical biochemistry, clinical microbiology, clinical immunology, and clinical genetics ¿ Transfusion Science ¿ Quality Management ¿ Near-patient testing (NPT)/Point of Care Testing
This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics across the life span: ¿ Human Anatomy and Physiology ¿ across the life span ¿ Good laboratory practice and Sustainability ¿ Key principles of cellular pathology, clinical biochemistry, clinical medicalmicrobiology, clinical immunology, clinical genetics and haematology ¿ Quality Management
This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study.
This module builds on the knowledge and skills developed in teaching components in part one of their relevant programme. Students will work independently in order to critically explore and add to the evidence base for a topic of relevance to their area of study.
2008 - Present
Siân-Eleri has established links with the National Botanic Garden of Wales. Where she carries out numerous bilingual science activities for primary school children, for example at the Garden’s science week.
