Dr Amy Johnson

Lecturer in Biomedical Science

Biomedical Sciences

a.l.johnson@swansea.ac.uk

Basic Welsh Speaker

Academic Office - 140
First Floor
Institute of Life Science 1
Singleton Campus

Available For Postgraduate Supervision

Research Links

ResearchGate

About

Dr Amy Johnson is a Lecturer of Biomedical Science at Swansea University Medical School.

Dr Johnson completed a Bsc (Hons) in Biomedical Science in 2006 and was awarded a Ph.D from Swansea University Medical School in 2011 investigating the Neuroimmune Modulation of the Circadian Clock. Dr Johnson then pursued a number of post-doctoral positions at Swansea University Medical School investigating the neuroprotective role of metabolic peptides in age-related diseases of the brain. She has strong interests in several areas of Neuroscience including Neurodegeneration, Neuroprotection and Neurogenesis. A lecturer at

Dr Johnson lectures on the postgraduate Msc Biomedical Science and specialises in Cellular Pathology. She is a fellow of the Institute of Biomedical Science.

Dr Johnson is also passionate about promoting industrial academic collaborations having spent 10 years in industry.

Areas Of Expertise

Neuroimmunology
Neurodegeneration
Neuroprotection
Cellular Pathology

Career Highlights

Teaching Interests

Dr Johnson lectures on the Biomedical Science (Clinical Biochemistry/Microbiology), MSc/PGDip degree programmes. Dr Johnson’s teaching focuses on Cellular Pathology and the laboratory techniques involved in Diagnostic Histopathology. In addition Dr Johnson helps to train students on their research projects.

Publications

Research Highlights

Johnson, A., Beynon, A., Brown, M., Wright, R., Rees, M., Sheldon, I., Davies, J., Brown, R., & Sheldon, M. (2013). Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones. Journal of Neuroinflammation, 10(1), 40
https://doi.org/10.1186/1742-2094-10-40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14452
Johnson, A., Kent, B., Beynon, A., Hornsby, A., Bekinschtein, P., Bussey, T., Davies, J., & Saksida, L. (2014). The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation. Psychoneuroendocrinology, 51, 431-439.
https://doi.org/10.1016/j.psyneuen.2014.10.015, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19690
http://www.sciencedirect.com/science/article/pii/S0306453014003990
Johnson, A., Ratcliff, M., Rees, D., McGrady, S., Buntwal, L., Hornsby, A., Bayliss, J., Kent, B., Bussey, T., Saksida, L., Beynon, A., Howell, O., Morgan, A., Sun, Y., Andrews, Z., Wells, T., & Davies, J. (2019). Calorie restriction activates new adult born olfactory‐bulb neurones in a ghrelin‐dependent manner but acyl‐ghrelin does not enhance subventricular zone neurogenesis. Journal of Neuroendocrinology, 31(7)
https://doi.org/10.1111/jne.12755, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51124
Johnson, A., Rees, D., Beynon, A., Lelos, M., Smith, G., Roberts, L., Phelps, L., Dunnett, S., Morgan, A., Brown, R., Wells, T., & Davies, J. (2022). Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease. Cellular and Molecular Neurobiology, 43
https://doi.org/10.1007/s10571-022-01282-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59475
Johnson, A., Quintela, M., James, D., Garcia, J., Edwards, K., Margarit, L., Das, N., Lutchman-Singh, K., Beynon, A., Rioja, I., Prinjha, R., Harker, N., Gonzalez, D., Conlan, S., & Francis, L. (2023). In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer. British Journal of Cancer, 129(1), 163-174.
https://doi.org/10.1038/s41416-023-02274-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63224
http://dx.doi.org/10.1038/s41416-023-02274-2
Quintela Vazquez, M., James, D., Baseviciene, A., Powell, L., Edwards, K., Coombes, Z., Garcia, J., Garton, N., Das, N., Lutchman-Singh, K., Margarit, L., Beynon, A., Rioja, I., Prinjha, R., Harker, N., Gonzalez, D., Conlan, S., Francis, L., & Johnson, A. (2023). Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells. Clinical Epigenetics, 15(1)
https://doi.org/10.1186/s13148-023-01477-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64098

All Research

Journal Articles

Johnson, A., Quintela, M., James, D., Garcia, J., Edwards, K., Margarit, L., Das, N., Lutchman-Singh, K., Beynon, A., Rioja, I., Prinjha, R., Harker, N., Gonzalez, D., Conlan, S., & Francis, L. (2023). In silico enhancer mining reveals SNS-032 and EHMT2 inhibitors as therapeutic candidates in high-grade serous ovarian cancer. British Journal of Cancer, 129(1), 163-174.
https://doi.org/10.1038/s41416-023-02274-2, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63224
http://dx.doi.org/10.1038/s41416-023-02274-2
Quintela Vazquez, M., James, D., Baseviciene, A., Powell, L., Edwards, K., Coombes, Z., Garcia, J., Garton, N., Das, N., Lutchman-Singh, K., Margarit, L., Beynon, A., Rioja, I., Prinjha, R., Harker, N., Gonzalez, D., Conlan, S., Francis, L., & Johnson, A. (2023). Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells. Clinical Epigenetics, 15(1)
https://doi.org/10.1186/s13148-023-01477-x, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa64098
Johnson, A., Rees, D., Beynon, A., Lelos, M., Smith, G., Roberts, L., Phelps, L., Dunnett, S., Morgan, A., Brown, R., Wells, T., & Davies, J. (2022). Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease. Cellular and Molecular Neurobiology, 43
https://doi.org/10.1007/s10571-022-01282-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59475
Johnson, A., Ratcliff, M., Rees, D., McGrady, S., Buntwal, L., Hornsby, A., Bayliss, J., Kent, B., Bussey, T., Saksida, L., Beynon, A., Howell, O., Morgan, A., Sun, Y., Andrews, Z., Wells, T., & Davies, J. (2019). Calorie restriction activates new adult born olfactory‐bulb neurones in a ghrelin‐dependent manner but acyl‐ghrelin does not enhance subventricular zone neurogenesis. Journal of Neuroendocrinology, 31(7)
https://doi.org/10.1111/jne.12755, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51124
Johnson, A., Kent, B., Beynon, A., Hornsby, A., Bekinschtein, P., Bussey, T., Davies, J., & Saksida, L. (2014). The orexigenic hormone acyl-ghrelin increases adult hippocampal neurogenesis and enhances pattern separation. Psychoneuroendocrinology, 51, 431-439.
https://doi.org/10.1016/j.psyneuen.2014.10.015, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa19690
http://www.sciencedirect.com/science/article/pii/S0306453014003990
Johnson, A., Beynon, A., Brown, M., Wright, R., Rees, M., Sheldon, I., Davies, J., Brown, R., & Sheldon, M. (2013). Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones. Journal of Neuroinflammation, 10(1), 40
https://doi.org/10.1186/1742-2094-10-40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14452

Taught Modules

PMBM04 Fundamentals of Biomedical Sciences 2

This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics across the life span: ¿ Human Anatomy and Physiology ¿ Pharmacology and Toxicology ¿ Key principles of cell pathology, clinical biochemistry, clinical microbiology, clinical immunology, and clinical genetics ¿ Transfusion Science ¿ Quality Management ¿ Near-patient testing (NPT)/Point of Care Testing
PMBM05J Fundamentals of Biomedical Sciences 1

This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics: ¿ Human Anatomy and Physiology ¿ Pharmacology and Toxicology ¿ Good laboratory practice and Sustainability ¿ Key principles of clinical biochemistry, clinical microbiology, clinical immunology, and clinical genetics ¿ Transfusion Science ¿ Quality Management ¿ Near-patient testing (NPT)/Point of Care Testing
PMBM06J Fundamentals of Biomedical Sciences 2

This module has been designed to provide students with the fundamental knowledge and principle concepts of biomedical science from a scientific and practice basis. The module will cover the following key topics across the life span: ¿ Human Anatomy and Physiology ¿ across the life span ¿ Cellular biology from structure to pathology ¿ Good laboratory practice and Sustainability ¿ Key principles of cell pathology, clinical biochemistry, clinical microbiology, clinical immunology, clinical genetics and haematology ¿ Clinical Pathology ¿ Quality Management

Career History

Business and Technical Development Manager, Porvair Sciences, Wrexham, UK

2017 - 2023
Product Development Manager, Chromatrap, Porvair Sciences at Swansea University

2013 - 2017
Post Doctoral Research Assistant, Molecular Neuroscience, Swansea University Medical School

2011 - 2013
Epigenetic Research Assistant, Active Motif Europe, Belgium SA

2008 - 2009

Other Roles

Chair of Collaborative Research Working Group (GUICC), GAMBICA

2023 - Present
Member of Gambica University Industrial Collaboration Council , GAMBICA

2020 - Present

Public Engagements

Dr Johnson is a STEM ambassador and regularly promotes and participates in local science related events.

Dr Amy Johnson

Email address

Welsh language proficiency

LinkedIn Account

Research Links

About

Areas Of Expertise

Career Highlights

Publications

Research Highlights

All Research

Journal Articles

Taught Modules

PMBM04 Fundamentals of Biomedical Sciences 2

PMBM05J Fundamentals of Biomedical Sciences 1

PMBM06J Fundamentals of Biomedical Sciences 2

Career History

Business and Technical Development Manager, Porvair Sciences, Wrexham, UK

Product Development Manager, Chromatrap, Porvair Sciences at Swansea University

Post Doctoral Research Assistant, Molecular Neuroscience, Swansea University Medical School

Epigenetic Research Assistant, Active Motif Europe, Belgium SA

Other Roles

Chair of Collaborative Research Working Group (GUICC), GAMBICA

Member of Gambica University Industrial Collaboration Council , GAMBICA

Public Engagements