Dr Rowan Brown

Athro Cyswllt

Biomedical Engineering

+44 (0) 1792 295206

m.r.brown@abertawe.ac.uk

417
Pedwerydd Llawr
Adeilad Gogleddol Peirianneg
Campws y Bae

Ar gael ar gyfer Goruchwyliaeth Ôl-raddedig

Dolenni Ymchwil

https://orcid.org/0000-0003-3628-2524

Trosolwg

Cytometreg Systemau/Microsgopeg

Mae technegau arbrofol trwybwn uchel, megis cytometreg llif, yn darparu gwybodaeth fanwl am nodweddion cylch celloedd ar gyfer poblogaethau cellog ar raddfa fawr (h.y. > 104 cell). Mae'r grŵp Cytometreg Systemau, a ffurfiwyd fel cynghrair rhwng prifysgolion Abertawe a Chaerdydd, yn defnyddio technegau efelychu stocastig amrywiol i ddehongli mesuriadau arbrofol sy'n caniatáu eglurhad ac esboniad o ymateb ac adferiad celloedd i asiantau ffarmacodynamig dros genedlaethau lluosog.

Ceulo Gwaed

Mae meintioli clot gwaed yn eithriadol o bwysig i fonitro a thrin clefydau ac anhwylderau gwaed. Ar hyn o bryd, nid oes unrhyw fesur o geulo gwaed sy’n cael ei dderbyn gan bawb yn bodoli. Yma yn Abertawe rydym wedi defnyddio, ac yn parhau i ddefnyddio mesurau sy'n seiliedig ar ffractalau i roi gwybod am ffurfiau clotiau dechreuol a rhai aeddfed. Mae'r mesurau hyn yn rhoi mewnwelediad ar drefniant gofodol màs a chymhlethdod y clotiau dilynol.

Rhaglennu Esblygiadol

Mae tarddiad llawer o strategaethau esblygol sy'n seiliedig ar y boblogaeth mewn prosesau biolegol corfforol; yma yn Abertawe rydym yn datblygu optimeiddiwyr amgen ac ategol ac yn ceisio defnyddio'r rhain i ddatrys problemau optimeiddio 'bywyd go iawn'.

Meysydd Arbenigedd

Dadansoddiad Stocastig
Bioleg Systemau
Cytometreg
Cyfrifiadura Esblygiadol
Dadansoddiad/Efelychiad Data Deallus ar Raddfa Fawr
Cynhyrchu a Dadansoddi Ffractal

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Wilde, E., Chapman, K., Stannard, L., Seager, A., Brüsehafer, K., Shah, U., Tonkin, J., Brown, M., Verma, J., Doherty, A., Johnson, G., Doak, S., Jenkins, G., Johnson, G., Jenkins, G., & Brown, R. (2018). A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells. Archives of Toxicology, 92(2), 935-951.
https://doi.org/10.1007/s00204-017-2102-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36828
Brown, R. & Rees, P. (2016). An Analysis of the Practicalities of Multi-Color Nanoparticle Cellular Bar-Coding. Combinatorial Chemistry & High Throughput Screening, 19(5), 362-369.
https://doi.org/10.2174/1386207319666160408150649, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28258
COBLEY, R., TENG, K., BROWN, M., MAFFEÏS, T., WILKS, S., Teng, V., & Brown, R. (2004). CROSS-SECTIONAL SCANNING TUNNELING MICROSCOPY OF BURIED HETEROSTRUCTURE LASERS. International Journal of Nanoscience, 03(04n05), 525-531.
https://doi.org/10.1142/S0219581X04002334, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28282
http://www.scopus.com/inward/record.url?eid=2-s2.0-10644283900&partnerID=MN8TOARS
Brown, M., Teng, K., Kestle, A., Smowton, P., Blood, P., Mawby, P., Wilks, S., Teng, V., & Brown, R. (2004). Study of dual-valley transport across a multiquantum barrier to enhance carrier confinement. Applied Surface Science, 234(1-4), 434-438.
https://doi.org/10.1016/j.apsusc.2004.05.074, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28280
http://www.scopus.com/inward/record.url?eid=2-s2.0-3343008910&partnerID=MN8TOARS
Walton, S., Hassan, O., Morgan, K., Brown, M., & Brown, R. (2013). Swarm Intelligence and Bio-Inspired Computation
https://doi.org/10.1016/B978-0-12-405163-8.00011-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28267
http://www.scopus.com/inward/record.url?eid=2-s2.0-84883921803&partnerID=MN8TOARS
Griesdoorn, V., Brown, M., Wiltshire, M., Smith, P., Errington, A., & Brown, R. (2016). Cell Cycle Oscillators (1st ed.). Springer.
https://doi.org/10.1007/978-1-4939-2957-3_17, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28263
http://www.scopus.com/inward/record.url?eid=2-s2.0-84938852215&partnerID=MN8TOARS
Brown, M., Hondow, N., Brydson, R., Rees, P., Brown, A., Summers, H., & Brown, R. (2015). Statistical prediction of nanoparticle delivery: from culture media to cell. Nanotechnology, 26(15), 155101
https://doi.org/10.1088/0957-4484/26/15/155101, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20639
Summers, H., Wills, J., Brown, M., Rees, P., & Brown, R. (2015). Poisson-event-based analysis of cell proliferation. Cytometry Part A, n/a-n/a.
https://doi.org/10.1002/cyto.a.22620, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20635
Hondow, N., Brown, A., Summers, H., Rowan Brown, M., Rees, P., Holton, M., Brydson, R., & Brown, R. (2014). Quantifying Nanoparticle–Cell Interactions. Microscopy and Microanalysis, 20(S3), 1300-1301.
https://doi.org/10.1017/S143192761400823X, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20629
Tonkin, J., Serda, R., Brown, M., Summers, H., Shamsudeen, S., Rees, P., & Brown, R. (2014). Optical tracking of drug release from porous silicon delivery vectors. IET Optoelectronics, 8(2), 113-116.
https://doi.org/10.1049/iet-opt.2013.0080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20628

Holl Ymchwil

Erthyglau Cylchgronau

Jones, S., Scott, G., Mara, J., Brown, R., & Bezodis, N. (2024). The importance of place-kicking in Women's International Rugby Union. Journal of Sports Sciences, 42(10), 865-873.
https://doi.org/10.1080/02640414.2024.2363704, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa66879
Scott, G., Bezodis, N., Waldron, M., Bennett, M., Church, S., Kilduff, L., & Brown, R. (2023). Performance indicators associated with match outcome within the United Rugby Championship. Journal of Science and Medicine in Sport, 26(1), 63-68.
https://doi.org/10.1016/j.jsams.2022.11.006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62102
Jarvis, D., Pope, E., Duteil, M., Furtbauer, I., Brown, R., Davis, R., & King, A. (2022). Elevated CO does not alter behavioural lateralization in free‐swimming juvenile European sea bass (Dicentrarchus labrax ) tested in groups. Journal of Fish Biology, 101(5), 1361-1365.
https://doi.org/10.1111/jfb.15180, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa61446
http://dx.doi.org/10.1111/jfb.15180
Johnson, A., Rees, D., Beynon, A., Lelos, M., Smith, G., Roberts, L., Phelps, L., Dunnett, S., Morgan, A., Brown, R., Wells, T., & Davies, J. (2022). Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease. Cellular and Molecular Neurobiology, 43
https://doi.org/10.1007/s10571-022-01282-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59475
Georgopoulou, D., King, A., Brown, R., & Fuertbauer, I. (2022). Emergence and repeatability of leadership and coordinated motion in fish shoals. Behavioral Ecology, 33(1), 47-54.
https://doi.org/10.1093/beheco/arab108, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57907
Wilson, R., Rose, K., Metcalfe, R., Holton, M., Redcliffe, J., Gunner, R., Borger, L., Loison, A., Jezek, M., Painter, M., Silovský, V., Marks, N., Garel, M., Toïgo, C., Marchand, P., Bennett, N., McNarry, M., Mackintosh, K., Brown, R., & SCANTLEBURY, D. (2021). Path tortuosity changes the transport cost paradigm in terrestrial animals. Ecography, 44(10)
https://doi.org/10.1111/ecog.05850, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57321
Munden, R., Borger, L., Wilson, R., Redcliffe, J., Brown, R., Garel, M., & Potts, J. (2021). Why did the animal turn? Time‐varying step selection analysis for inference between observed turning‐points in high frequency data. Methods in Ecology and Evolution, 12(5), 921-932.
https://doi.org/10.1111/2041-210x.13574, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57055
James, D., Filby, A., Brown, R., Summers, H., Francis, L., & Rees, P. (2021). Data Driven Cell Cycle Model to Quantify the Efficacy of Cancer Therapeutics Targeting Specific Cell-Cycle Phases From Flow Cytometry Results. Frontiers in Bioinformatics, 1
https://doi.org/10.3389/fbinf.2021.662210, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56655
Waldron, M., Jones, C., Melotti, L., Brown, R., & Kilduff, L. (2021). Collision monitoring in elite male rugby union using a new instrumented mouth-guard. The Journal of Sport and Exercise Science, 5(3), 179-187.
https://doi.org/10.36905/jses.2021.03.03, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56455
Chapman, K., Wilde, E., Chapman, F., Verma, J., Shah, U., Stannard, L., Seager, A., Tonkin, J., Brown, R., Doherty, A., Johnson, G., Doak, S., & Jenkins, G. (2021). Multiple-endpoint in vitro carcinogenicity test in human cell line TK6 distinguishes carcinogens from non-carcinogens and highlights mechanisms of action. Archives of Toxicology, 95(1), 321-336.
https://doi.org/10.1007/s00204-020-02902-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55186
Shah, U., Verma, J., Chapman, K., Wilde, E., Tonkin, J., Brown, R., Johnson, G., Doak, S., & Jenkins, G. (2020). Detection of urethane-induced genotoxicity in vitro using metabolically competent human 2D and 3D spheroid culture models. Mutagenesis, 35(6), 445-452.
https://doi.org/10.1093/mutage/geaa029, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55770
Greybe, D., Jones, C., Brown, R., & Williams, E. (2020). Comparison of head impact measurements via an instrumented mouthguard and an anthropometric testing device. Sports Engineering, 23(1)
https://doi.org/10.1007/s12283-020-00324-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54405
http://dx.doi.org/10.1007/s12283-020-00324-z
Rees, D., Roberts, L., Carisi, C., Morgan, A., Brown, R., & Davies, J. (2020). Automated Quantification of Mitochondrial Fragmentation in an In Vitro Parkinson's Disease Model. Current Protocols in Neuroscience, 94(1)
https://doi.org/10.1002/cpns.105, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55596
Thomas, B., Hambly, R., Weisel, J., Rauova, L., Badiei, N., Brown, R., Thornton, C., Williams, R., & Hawkins, K. (2020). Abnormal clot microstructure formed in blood containing HIT-like antibodies. Thrombosis Research, 193, 25-30.
https://doi.org/10.1016/j.thromres.2020.05.029, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54403
Rees, D., Roberts, L., Carisi, C., Morgan, A., Brown, R., & Davies, J. (2020). Automated Quantification of Mitochondrial Fragmentation in an In-Vitro Parkinson’s Disease Model (Pre-print version). BioRxiv
https://doi.org/10.1101/2020.05.15.093369, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54322
Fuertbauer, I., Brown, R., & Heistermann, M. (2020). Collective action reduces androgen responsiveness with implications for shoaling dynamics in stickleback fish. Hormones and Behavior, 119, 104636
https://doi.org/10.1016/j.yhbeh.2019.104636, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa52635
http://dx.doi.org/10.1016/j.yhbeh.2019.104636
Rees, P., Wills, J., Brown, R., Barnes, C., & Summers, H. (2019). The origin of heterogeneous nanoparticle uptake by cells. Nature Communications, 10(1)
https://doi.org/10.1038/s41467-019-10112-4, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50105
http://dx.doi.org/10.1038/s41467-019-10112-4
Walton, S. & Brown, R. (2019). Predicting effective control parameters for differential evolution using cluster analysis of objective function features. Journal of Heuristics, 25(6), 1015-1031.
https://doi.org/10.1007/s10732-019-09419-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa50868
http://dx.doi.org/10.1007/s10732-019-09419-8
Wilde, E., Chapman, K., Stannard, L., Seager, A., Brüsehafer, K., Shah, U., Tonkin, J., Brown, M., Verma, J., Doherty, A., Johnson, G., Doak, S., Jenkins, G., Johnson, G., Jenkins, G., & Brown, R. (2018). A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells. Archives of Toxicology, 92(2), 935-951.
https://doi.org/10.1007/s00204-017-2102-y, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa36828
Brown, R. & Rees, P. (2016). An Analysis of the Practicalities of Multi-Color Nanoparticle Cellular Bar-Coding. Combinatorial Chemistry & High Throughput Screening, 19(5), 362-369.
https://doi.org/10.2174/1386207319666160408150649, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28258
Lawrence, M., Marsden, N., Kaczynski, J., Davies, G., Davies, N., Hawkins, K., Perumal, S., Brown, M., Morris, K., Davidson, S., Williams, P., Evans, P., Brown, R., & Evans, A. (2016). An Investigation Into the Effects of In Vitro Dilution With Different Colloid Resuscitation Fluids on Clot Microstructure Formation. Anesthesia & Analgesia, 1
https://doi.org/10.1213/ANE.0000000000001536, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30371
Davies, G., Pillai, S., Lawrence, M., Mills, G., Aubrey, R., D´Silva, L., Battle, C., Williams, R., Brown, R., Thomas, D., Morris, K., & Evans, A. (2016). The effect of sepsis and its inflammatory response on mechanical clot characteristics: a prospective observational study. Intensive Care Medicine, 42(12), 1990-1998.
https://doi.org/10.1007/s00134-016-4496-z, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30088
Duteil, M., Pope, E., Pérez-Escudero, A., de Polavieja, G., Fürtbauer, I., Brown, M., King, A., Pope, E., Brown, R., King, A., & Fuertbauer, I. (2016). European sea bass show behavioural resilience to near-future ocean acidification. Royal Society Open Science, 3(11), 160656
https://doi.org/10.1098/rsos.160656, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa30902
Lawrence, M., Marsden, N., Mothukuri, R., Morris, R., Davies, G., Hawkins, K., Curtis, D., Brown, M., Williams, P., Evans, P., Williams, R., Brown, R., & Evans, A. (2016). The Effects of Temperature on Clot Microstructure and Strength in Healthy Volunteers. Anesthesia & Analgesia, 122(1), 21-26.
https://doi.org/10.1213/ANE.0000000000000992, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27872
http://www.scopus.com/inward/record.url?eid=2-s2.0-84951567216&partnerID=MN8TOARS
HONDOW, N., BROWN, M., STARBORG, T., MONTEITH, A., BRYDSON, R., Summers, H., Rees, P., BROWN, A., & Brown, R. (2016). Quantifying the cellular uptake of semiconductor quantum dot nanoparticles by analytical electron microscopy. Journal of Microscopy, n/a-n/a.
https://doi.org/10.1111/jmi.12239, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20508
Summers, H., Wills, J., Brown, M., Rees, P., & Brown, R. (2015). Poisson-event-based analysis of cell proliferation. Cytometry Part A, n/a-n/a.
https://doi.org/10.1002/cyto.a.22620, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20635
Stanford, S., Sabra, A., D’Silva, L., Lawrence, M., Morris, R., Storton, S., Brown, M., Evans, V., Hawkins, K., Williams, P., Davidson, S., Wani, M., Potter, J., Evans, P., Williams, R., Brown, R., & Evans, A. (2015). The changes in clot microstructure in patients with ischaemic stroke and the effects of therapeutic intervention: a prospective observational study. BMC Neurology, 15(1)
https://doi.org/10.1186/s12883-015-0289-1, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20524
Broome, L., Davies, N., Harrison, N., Morris, R., Noble, S., Lawrence, M., D'Silva, L., Broome, L., Brown, R., Hawkins, K., Williams, R., Davidson, S., & Evans, A. (2015). Fractal dimension (df) as a new structural biomarker of clot microstructure in different stages of lung cancer. Thrombosis and Haemostasis, 114(6), 1251-1259.
https://doi.org/10.1160/TH15-04-0357, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa22970
King, A., Myatt, J., Fürtbauer, I., Oesch, N., Dunbar, R., Sumner, S., Usherwood, J., Hailes, S., Brown, M., Brown, R., & Fuertbauer, I. (2015). Social density processes regulate the functioning and performance of foraging human teams. Scientific Reports, 5, 18260
https://doi.org/10.1038/srep18260, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25129
http://www.nature.com/articles/srep18260
James, D., Higgins, A., Rees, P., Geoghegan, M., Brown, M., Chang, S., Môn, D., Cubitt, R., Dalgliesh, R., Gutfreund, P., & Brown, R. (2015). Measurement of molecular mixing at a conjugated polymer interface by specular and off-specular neutron scattering. Soft Matter, 11(48), 9393-9403.
https://doi.org/10.1039/C5SM02008E, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa26063
Badiei, N., Sowedan, A., Curtis, D., Brown, R., Lawrence, M., Campbell, A., Sabra, A., Evans, A., Weisel, J., Chernysh, I., Nagaswami, C., Williams, R., & Hawkins, K. (2015). Effects of unidirectional flow shear stresses on the formation, fractal microstructure and rigidity of incipient whole blood clots and fibrin gels. Clinical Hemorheology and Microcirculation, 60(4), 451-464.
https://doi.org/10.3233/ch-151924, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20275
Curtis, D., Holder, A., Badiei, N., Claypole, J., Walters, M., Thomas, B., Barrow, M., Deganello, D., Brown, R., Williams, R., & Hawkins, K. (2015). Validation of Optimal Fourier Rheometry for rapidly gelling materials and its application in the study of collagen gelation. Journal of Non-Newtonian Fluid Mechanics, 222, 253-259.
https://doi.org/10.1016/j.jnnfm.2015.01.003, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20273
http://dx.doi.org/10.1016/j.jnnfm.2015.01.003
Curtis, D., Badiei, N., Holder, A., Claypole, J., Deganello, D., Brown, R., Lawrence, M., Evans, A., Williams, R., & Hawkins, K. (2015). Assessment of the stress relaxation characteristics of critical gels formed under unidirectional shear flow by controlled stress parallel superposition rheometry. Journal of Non-Newtonian Fluid Mechanics, 222, 227-233.
https://doi.org/10.1016/j.jnnfm.2014.12.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20274
Lawrence, M., Sabra, A., Thomas, P., Obaid, D., D´Silva, L., Morris, R., Hawkins, K., Brown, R., Williams, R., Davidson, S., Chase, A., Smith, D., & Evans, A. (2015). Fractal dimension: A novel clot microstructure biomarker use in ST elevation myocardial infarction patients. Atherosclerosis, 240(2), 402-407.
https://doi.org/10.1016/j.atherosclerosis.2015.04.012, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27876
Brown, M., Hondow, N., Brydson, R., Rees, P., Brown, A., Summers, H., & Brown, R. (2015). Statistical prediction of nanoparticle delivery: from culture media to cell. Nanotechnology, 26(15), 155101
https://doi.org/10.1088/0957-4484/26/15/155101, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20639
Lawrence, M., Sabra, A., Mills, G., Pillai, S., Abdullah, W., Hawkins, K., Morris, R., Davidson, S., D´Silva, L., Curtis, D., Brown, R., Weisel, J., Williams, R., & Evans, A. (2015). A new biomarker quantifies differences in clot microstructure in patients with venous thromboembolism. British Journal of Haematology, 168(4), 571-575.
https://doi.org/10.1111/bjh.13173, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa27555
Hondow, N., Brown, A., Summers, H., Rowan Brown, M., Rees, P., Holton, M., Brydson, R., & Brown, R. (2014). Quantifying Nanoparticle–Cell Interactions. Microscopy and Microanalysis, 20(S3), 1300-1301.
https://doi.org/10.1017/S143192761400823X, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20629
Tonkin, J., Serda, R., Brown, M., Summers, H., Shamsudeen, S., Rees, P., & Brown, R. (2014). Optical tracking of drug release from porous silicon delivery vectors. IET Optoelectronics, 8(2), 113-116.
https://doi.org/10.1049/iet-opt.2013.0080, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20628
Lawrence, M., Kumar, S., Hawkins, K., Boden, S., Rutt, H., Mills, G., Sabra, A., Morris, R., Davidson, S., Badiei, N., Brown, M., Williams, P., Evans, P., Williams, R., Brown, R., & Evans, A. (2014). A new structural biomarker that quantifies and predicts changes in clot strength and quality in a model of progressive haemodilution. Thrombosis Research, 134(2), 488-494.
https://doi.org/10.1016/j.thromres.2014.05.039, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa18269
Davies, N., Holland, P., Brown, R., & Summers, H. (2014). Development of an Optically Transparent Silicon CMOS Technology Platform for Biological Analysis. IEEE Sensors Journal, 1-1.
https://doi.org/10.1109/JSEN.2014.2367238, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20571
Rees, P., Wills, J., Brown, R., Tonkin, J., Holton, M., Hondow, N., Brown, A., Brydson, R., Millar, V., Carpenter, A., & Summers, H. (2014). Nanoparticle vesicle encoding for imaging and tracking cell populations. Nature Methods, 11(11), 1177-1181.
https://doi.org/10.1038/nmeth.3105, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa20509
Summers, H., Brown, M., Holton, M., Tonkin, J., Hondow, N., Brown, A., Brydson, R., Rees, P., & Brown, R. (2013). Quantification of Nanoparticle Dose and Vesicular Inheritance in Proliferating Cells. ACS Nano, 7(7), 6129-6137.
https://doi.org/10.1021/nn4019619, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa15846
Johnson, A., Beynon, A., Brown, M., Wright, R., Rees, M., Sheldon, I., Davies, J., Brown, R., & Sheldon, M. (2013). Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones. Journal of Neuroinflammation, 10(1), 40
https://doi.org/10.1186/1742-2094-10-40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14452
Walton, S., Brown, M., Hassan, O., Morgan, K., Hassan, O., Brown, R., & Walton, S. (2013). Comment on Cuckoo search: A new nature-inspired optimization method for phase equilibrium calculations by V. Bhargava, S. Fateen, A. Bonilla-Petriciolet. Fluid Phase Equilibria(352)-66.
https://doi.org/10.1016/j.fluid.2013.05.011, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa15568
http://www.sciencedirect.com/science/article/pii/S0378381213002240
Curtis, D., Williams, P., Badiei, N., Campbell, A., Hawkins, K., Evans, P., Brown, M., Williams, R., Brown, R., & Evans, A. (2013). A study of microstructural templating in fibrin-thrombin gel networks by spectral and viscoelastic analysis. Soft Matter, 9(19), 4883-4889.
https://doi.org/10.1039/C3SM50263E, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa14405
Brown, R., Rees, P., & Summers, H. (2012). Quantitative characterization of nanoparticle agglomeration within biological media. Journal of Nanoparticle Research, 14(7)
https://doi.org/10.1007/s11051-012-0977-3, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12659
Brown, R., Rees, P., & Summers, H. (2012). Automated Cell Identification and Tracking Using Nanoparticle Moving-Light-Displays. PLoS ONE, 7(7), e40835
https://doi.org/10.1371/journal.pone.0040835, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12930
Brown, M., Curtis, D., Rees, P., Summers, H., Hawkins, K., Evans, P., Williams, P., Williams, R., Hawkins, K., Brown, R., Rees, P., Summers, H., Curtis, D., & Evans, A. (2012). Fractal discrimination of random fractal aggregates and its application in biomarker analysis for blood coagulation. Chaos, Solitons & Fractals, 45(8), 1025-1032.
https://doi.org/10.1016/j.chaos.2012.04.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10968
Brown, R., Rees, P., & Summers, H. (2011). Statistical analysis of nanoparticle dosing in a dynamic cellular system. Nature Nanotechnology
https://doi.org/10.1038/nnano.2010.277, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5706
Brown, R., Rees, P., & Summers, H. (2011). A transfer function approach to measuring cell inheritance. BMC Systems Biology
https://doi.org/10.1186/1752-0509-5-31, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5707
Khan, I., Lupi, M., Campbell, L., Chappell, S., Brown, M., Wiltshire, M., Smith, P., Ubezio, P., Errington, R., & Brown, R. (2011). Interoperability of time series cytometric data: A cross platform approach for modeling tumor heterogeneity. Cytometry Part A, 79A(3), 214-226.
https://doi.org/10.1002/cyto.a.21023, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa6225
Walton, S., Hassan, O., Morgan, K., Brown, M., Morgan, K., Hassan, O., Brown, R., & Walton, S. (2011). Modified cuckoo search: A new gradient free optimisation algorithm. Chaos, Solitons & Fractals, 44(9), 710-718.
https://doi.org/10.1016/j.chaos.2011.06.004, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa6147
Curtis, D., Brown, M., Hawkins, K., Evans, P., Lawrence, M., Rees, P., Williams, P., Williams, R., Hawkins, K., Brown, R., Rees, P., Lawrence, M., Curtis, D., & Evans, A. (2011). Rheometrical and molecular dynamics simulation studies of incipient clot formation in fibrin-thrombin gels: An activation limited aggregation approach. Journal of Non-Newtonian Fluid Mechanics, 166(16), 932-938.
https://doi.org/10.1016/j.jnnfm.2011.04.016, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12137
Brown, R., Rees, P., & Summers, H. (2010). Flow-Based Cytometric Analysis of Cell Cycle via Simulated Cell Populations. PLoS Computational Biology
https://doi.org/10.1371/journal.pcbi.1000741, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5708
Brown, M., Summers, H., Rees, P., Chappell, S., Silvestre, O., Khan, I., Smith, P., Errington, R., & Brown, R. (2010). Long-term time series analysis of quantum dot encoded cells by deconvolution of the autofluorescence signal. Cytometry Part A, 77A(10), 925-932.
https://doi.org/10.1002/cyto.a.20936, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5711
Brown, M., Errington, R., Rees, P., Williams, P., Wilks, S., Wilks, S., Brown, R., & Rees, P. (2010). A highly efficient algorithm for the generation of random fractal aggregates. Physica D: Nonlinear Phenomena, 239(12), 1061-1066.
https://doi.org/10.1016/j.physd.2010.02.018, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5564
Evans, P., Lawrence, M., Morris, R., Thirumalai, N., Munro, R., Wakeman, L., Beddel, A., Williams, P., Barrow, M., Curtis, D., Brown, M., Hawkins, K., Williams, R., Brown, R., & Evans, A. (2010). Fractal analysis of viscoelastic data with automated gel point location and its potential application in the investigation of therapeutically modified blood coagulation. Rheologica Acta, 49(9), 901-908.
https://doi.org/10.1007/s00397-010-0472-7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10212
Rees, P., Brown, R., & Summers, H. (2010). Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance. Cell Cycle, 9(1)
https://doi.org/10.4161/cc.9.1.10246, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa10552
Cobley, R., Wilks, S., Teng, V., Brown, R., & Rees, P. (2010). Surface defects in semiconductor lasers studied with cross-sectional scanning tunneling microscopy. Applied Surface Science, 256(19), 5736
https://doi.org/10.1016/j.apsusc.2010.03.089, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5734
Maffeis, T. & Brown, R. (2009). Scanning Probe Microscopy of ZnO Nanobelts. e-Journal of Surface Science and Nanotechnology
https://doi.org/10.1380/ejssnt.2009.323, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5689
Wright, C., Wilks, S., Maffeis, T., & Brown, R. (2008). Atomic force microscopy and scanning tunneling microscopy-spectroscopy characterization of ZnO nanobelts. Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures
https://doi.org/10.1116/1.2838048, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5469
Ackland, M., Dunstan, P., Brown, M., Teng, K., Wilks, S., Cobley, R., Wilks, S., Dunstan, P., Teng, V., & Brown, R. (2008). Characterisation of the influence of multi-quantum barrier reflectors within GaInP/AlGaInP quantum well lasers using near-field imaging techniques. Applied Surface Science
https://doi.org/10.1016/j.apsusc.2008.07.062, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa5662
Cobley, R., Teng, K., Brown, M., Wilks, S., Rees, P., Wilks, S., Teng, V., Brown, R., Cobley, R., & Rees, P. (2007). Direct real-time observation of catastrophic optical degradation in operating semiconductor lasers using scanning tunneling microscopy. Applied Physics Letters, 91(8), 081119
https://doi.org/10.1063/1.2775049, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1828
Penny, M., Brown, M., Maffeïs, T., Rees, P., Wilks, S., Ferkel, H., Wilks, S., Brown, R., & Rees, P. (2007). Charge storage in SnO[sub 2] nanoparticles: A method and mechanism for charge writing/erasing. Applied Physics Letters, 91(16), 163108
https://doi.org/10.1063/1.2800891, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1831
Cobley, R., Teng, K., Brown, M., Wilks, S., Teng, V., Brown, R., & Cobley, R. (2007). Cross-sectional scanning tunneling microscopy of biased semiconductor lasers. Journal of Applied Physics, 102, 024306
https://doi.org/10.1063/1.2757006, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1852
Brown, M., Rees, P., Cobley, R., Teng, K., Wilks, S., Hughes, A., Teng, V., & Brown, R. (2007). The effect of interface roughness on multilayer heterostructures. Journal of Applied Physics, 102(11), 113711
https://doi.org/10.1063/1.2818108, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12713
Summers, H., Rees, P., Matthews, D., Edwards, G., Brown, M., Cundin, M., Dominguez, J., Lewis, G., Brown, R., Rees, P., & Summers, H. (2007). The Influence of the Gain—Carrier Density Characteristic on <formula formulatype="inline"><tex>$Q$</tex></formula>-Switching in Quantum-Dot Lasers. IEEE Journal of Selected Topics in Quantum Electronics, 13(5), 1222-1226.
https://doi.org/10.1109/JSTQE.2007.903853, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25328
http://www.scopus.com/inward/record.url?eid=2-s2.0-35348940749&partnerID=MN8TOARS
Brown, M., Rees, P., Wilks, S., Holton, M., Dunstan, P., Summers, H., Chong, Z., Brown, R., Rees, P., & Summers, H. (2007). Calculation of quantum-dot blinking using the Gillespie Monte Carlo algorithm. IET Optoelectronics, 1(6), 280-283.
https://doi.org/10.1049/iet-opt:20070044, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25341
http://www.scopus.com/inward/record.url?eid=2-s2.0-37249075869&partnerID=MN8TOARS
Brown, M., Cobley, R., Teng, K., Rees, P., Wilks, S., Sobiesierski, A., Smowton, P., Blood, P., Teng, V., Brown, R., Cobley, R., & Rees, P. (2006). Modeling multiple quantum barrier effects and reduced electron leakage in red-emitting laser diodes. Journal of Applied Physics, 100(8), 084509
https://doi.org/10.1063/1.2362906, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa6333
Sobiesierski, A., Sandall, I., Smowton, P., Blood, P., Krysa, A., Brown, M., Teng, K., Wilks, S., Wilks, S., Teng, V., & Brown, R. (2005). AlGaInP laser diodes incorporating a 3λ∕4 multiple quantum barrier. Applied Physics Letters, 86(2), 021102
https://doi.org/10.1063/1.1849847, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1830
Teng, K., Cobley, R., Brown, M., Wilks, S., Dunstan, P., Dunstan, P., Teng, V., Brown, R., & Cobley, R. (2005). Investigation on (Al0.7Ga0.3)(0.5)In0.5P/(Al0.3Ga0.7)(0.5)In0.5P multi-quantum-barrier superlattice using cross-sectional scanning tunneling microscopy. Journal of Applied Physics, 98, 033525
https://doi.org/10.1063/1.2005375, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1854
COBLEY, R., TENG, K., BROWN, M., MAFFEÏS, T., WILKS, S., Teng, V., & Brown, R. (2004). CROSS-SECTIONAL SCANNING TUNNELING MICROSCOPY OF BURIED HETEROSTRUCTURE LASERS. International Journal of Nanoscience, 03(04n05), 525-531.
https://doi.org/10.1142/S0219581X04002334, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28282
http://www.scopus.com/inward/record.url?eid=2-s2.0-10644283900&partnerID=MN8TOARS
Brown, M., Teng, K., Kestle, A., Smowton, P., Blood, P., Mawby, P., Wilks, S., Teng, V., & Brown, R. (2004). Study of dual-valley transport across a multiquantum barrier to enhance carrier confinement. Applied Surface Science, 234(1-4), 434-438.
https://doi.org/10.1016/j.apsusc.2004.05.074, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28280
http://www.scopus.com/inward/record.url?eid=2-s2.0-3343008910&partnerID=MN8TOARS
Teng, K., Brown, M., Wilks, S., Sobiesierski, A., Smowton, P., Blood, P., Teng, V., & Brown, R. (2004). Impurity-induced disordering in AlGaInP superlattices studied using cross-sectional scanning tunneling microscopy. Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures, 22(4), 2014
https://doi.org/10.1116/1.1768187, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12724
Teng, K., Brown, M., Kestle, A., Smowton, P., Blood, P., Pinches, S., Mawby, P., Wilks, S., Teng, V., & Brown, R. (2002). An investigation of multi-quantum barriers for band offset engineering in AlGaInP/GaInP lasers. Applied Surface Science, 190(1-4), 284-287.
https://doi.org/10.1016/S0169-4332(01)00869-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa12725
Scott, G., Edwards, O., Bezodis, N., Waldron, M., Roberts, E., Pyne, D., Mara, J., Cook, C., Mason, L., Brown, R., & Kilduff, L. (n.d.) Classifying Winning Performances in International Women’s Rugby Union. International Journal of Sports Physiology and Performance, 18(9), 1-7.
https://doi.org/10.1123/ijspp.2023-0086, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa63875
http://dx.doi.org/10.1123/ijspp.2023-0086

Llyfrau Awdurol

Griesdoorn, V., Brown, M., Wiltshire, M., Smith, P., Errington, A., & Brown, R. (2016). Cell Cycle Oscillators (1st ed.). Springer.
https://doi.org/10.1007/978-1-4939-2957-3_17, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28263
http://www.scopus.com/inward/record.url?eid=2-s2.0-84938852215&partnerID=MN8TOARS
Walton, S., Hassan, O., Morgan, K., Brown, M., & Brown, R. (2013). Swarm Intelligence and Bio-Inspired Computation
https://doi.org/10.1016/B978-0-12-405163-8.00011-9, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa28267
http://www.scopus.com/inward/record.url?eid=2-s2.0-84883921803&partnerID=MN8TOARS

Penodau Llyfrau

Brown, M., Rees, P., Wilks, S., Summers, H., Errington, R., Njoh, K., Chappell, S., Smith, P., Leary, J., & Brown, R. (2007). Computational Simulation of Optical Tracking of Cell Populations Using Quantum Dot Fluorophores. Computational Methods in Systems Biology (pp. 96
https://doi.org/10.1007/978-3-540-75140-3_7, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa1867

Cyfraniadau Cynadleddau

Summers, H., Errington, R., Smith, P., Chappell, S., Rees, P., Brown, M., Leary, J., Brown, R., & Rees, P. (2008). Cell-population tracking using quantum dots in flow cytometry. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE
https://doi.org/10.1117/12.763602, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa25526
http://www.scopus.com/inward/record.url?eid=2-s2.0-42149161697&partnerID=MN8TOARS

Goruchwyliaeth

surface studies of gas sensing materials (cyfredol)

PhD

Goruchwyliwr arall: Dr Thierry Maffeis
Optimising data processing methods for the application of instrumented-mouthguards in sport. (cyfredol)

PhD

Goruchwyliwr arall: Dr Mark Waldron
Environmental and individual-level drivers of movements and space use in three ungulate species Déterminants environnementaux et individuels des mouvements et de l'utilisation de l'espace chez trois espèces d'ongulés sauvages. (dyfarnwyd 2023)

PhD

Goruchwyliwr arall: Prof Luca Borger
Novel anti-microbial metallic surfaces for infection control (cyfredol)

EngD

Goruchwyliwr arall: Dr Geertje Van Keulen
A MACHINE LEARNING AND DATA-DRIVEN ASSESSMENT MODEL FOR CHARACTERISING AND PREDICTING A TEAMS SUCCESS IN CHAMPIONSHIP FOOTBALL (dyfarnwyd 2023)

MSc

Goruchwyliwr arall: Prof Liam Kilduff
The assembly of novel collagens for regenerative medicine (cyfredol)

MSc

Goruchwyliwr arall: Dr Christopher Wright

Modiwlau a Addysgir

EG-000 Fundamentals of Engineering Design

This module provides the essential skills required for future design modules and project tasks by providing a firm grounding for teamwork and emphasizing the need for professional standards and strong communication skills within engineering.
EG-114 Engineering Mathematics 1 (Mech & EEE & Engineering)

This module (in combination with Engineering Analysis 2B) provides the essential grounding in mathematical analysis techniques for engineering students. This module ensures that all students have a suitable level of analytical skills for subsequent engineering modules.
EGA127 Engineering Mathematics (EEE, General and Mech)

This module provides the essential grounding in mathematical analysis techniques for Engineering students. This module ensures that all students have a suitable level of mathematical skills for subsequent engineering modules.
EGDM03 Individual Research Design Project

This module involves the application of advanced scientific and engineering principles to the solution of a practical problem coming from outside engineering. It mainly involves project to design solutions for complex biomedical engineering problems and evidences some originality and meets a combination of societal, user, business and customer needs as appropriate. This project will involve consideration of applicable health and safety, diversity, inclusion, cultural, societal, environmental and commercial matters, codes of practice and industry standards. The student will be working independently on a substantial, individually assigned research design, using accepted planning procedures. It will require and develop self-organisation and a critical evaluation of options and results, as well as developing technical knowledge in the topic of research design. The student will develop a clear view on the integration of biomedical engineering in a professional environment.

Dr Rowan Brown

Rhif ffôn

Cyfeiriad ebost

Dolenni Ymchwil

Trosolwg

Meysydd Arbenigedd

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Holl Ymchwil

Erthyglau Cylchgronau

Llyfrau Awdurol

Penodau Llyfrau

Cyfraniadau Cynadleddau

Goruchwyliaeth

surface studies of gas sensing materials (cyfredol)

Optimising data processing methods for the application of instrumented-mouthguards in sport. (cyfredol)

Environmental and individual-level drivers of movements and space use in three ungulate species Déterminants environnementaux et individuels des mouvements et de l'utilisation de l'espace chez trois espèces d'ongulés sauvages. (dyfarnwyd 2023)

Novel anti-microbial metallic surfaces for infection control (cyfredol)

A MACHINE LEARNING AND DATA-DRIVEN ASSESSMENT MODEL FOR CHARACTERISING AND PREDICTING A TEAMS SUCCESS IN CHAMPIONSHIP FOOTBALL (dyfarnwyd 2023)

The assembly of novel collagens for regenerative medicine (cyfredol)

Modiwlau a Addysgir

EG-000 Fundamentals of Engineering Design

EG-114 Engineering Mathematics 1 (Mech & EEE & Engineering)

EGA127 Engineering Mathematics (EEE, General and Mech)

EGDM03 Individual Research Design Project