Institute of Life Science 2 Internal Atrium

Dr Salvatore Gazze

Aelod Cyswllt

Faculty of Medicine Health and Life Science

s.a.gazze@abertawe.ac.uk

Trosolwg

Ar ôl ennill gradd MSc mewn Biotechnoleg Fferyllol ym Mhrifysgol Bologna, yr Eidal, cefais swydd gyda chwmni biofeddygol yn Sbaen i ymchwilio i fiosynhwyrydd newydd wedi'i seilio ar MEMS. Yn dilyn y profiad hwn, cwblheais fy noethuriaeth mewn nanowyddoniaeth ym Mhrifysgol Bryste, ac ar hyn o bryd rwy'n cymhwyso nanowyddoniaeth ar gyfer ymchwil biofeddygol o fewn grŵp ymchwil Bioleg Atgenhedlol ac Oncoleg Gynaecolegol (RBGO) ym Mhrifysgol Abertawe. Rwy’n cael fy swyno’n gyson gan ddarganfyddiadau newydd a chynnydd mewn gwyddoniaeth, gyda sylw arbennig i wyddoniaeth feddygol, ond hefyd i wyddoniaeth yn ei sbectrwm ehangach, o ffiseg a chemeg i beirianneg a chyfrifiadureg.

Meysydd Arbenigedd

Nanowyddoniaeth
Biosynwyryddion
Biogeogemeg
Dadansoddi data

Cyhoeddiadau

Uchafbwyntiau Ymchwil

Sawhney, M., Azzopardi, E., Rodrigues Teixeira, S., Francis, L., Conlan, R., Gazze, S., Conlan, S., & Gazze, S. (2019). Measuring the impact on impedance spectroscopy of pseudo-reference electrode accumulations. Electrochemistry Communications, 105, 106508
https://doi.org/10.1016/j.elecom.2019.106508, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51355
Gazze, A., Ademefun, R., Conlan, R., Teixeira, S., Conlan, S., & Gazze, S. (2018). Electrochemical impedence spectroscopy enabled CA125 detection; toward early ovarian cancer diagnosis using graphene biosensors. Journal of Interdisciplinary Nanomedicine, 3(2), 82-88.
https://doi.org/10.1002/jin2.40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43526
Friguglietti, J., Das, S., Le, P., Fraga, D., Quintela Vazquez, M., Gazze, S., McPhail, D., Gu, J., Sabek, O., Gaber, A., Francis, L., Zagozdzon-Wosik, W., & Merchant, F. (2020). Novel Silicon Titanium Diboride Micropatterned Substrates for Cellular Patterning. Biomaterials, 244, 119927
https://doi.org/10.1016/j.biomaterials.2020.119927, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54548
Toubhans, B., Gazze, S., Bissardon, C., Bohic, S., Gourlan, A., Gonzalez, D., Charlet, L., Conlan, S., & Francis, L. (2020). Selenium nanoparticles trigger alterations in ovarian cancer cell biomechanics. Nanomedicine: Nanotechnology, Biology and Medicine, 29, 102258
https://doi.org/10.1016/j.nano.2020.102258, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54635
Pisano, S., Wang, X., Garcia Parra, J., Gazze, S., Edwards, K., Feltracco, V., Hu, Y., He, L., Gonzalez, D., Francis, L., Conlan, S., & Li, C. (2020). Nanomicelles potentiate histone deacetylase inhibitor efficacy in vitro. Cancer Nanotechnology, 11(1)
https://doi.org/10.1186/s12645-020-00070-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55789
Gazze, S., Thomas, S., Garcia-Parra, J., James, D., Rees, P., Marsh-Durban, V., Corteling, R., Gonzalez, D., Conlan, S., & Francis, L. (2021). High content, quantitative AFM analysis of the scalable biomechanical properties of extracellular vesicles. Nanoscale, 13(12), 6129-6141.
https://doi.org/10.1039/d0nr09235e, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56477
Edwards, K., Yao, S., Pisano, S., Feltracco, V., Bruesehafer, K., Samanta, S., Oommen, O., Gazze, S., Paravati, R., Maddison, H., Li, C., Gonzalez, D., Conlan, S., & Francis, L. (2021). Hyaluronic Acid-Functionalized Nanomicelles Enhance SAHA Efficacy in 3D Endometrial Cancer Models. Cancers, 13(16), 4032
https://doi.org/10.3390/cancers13164032, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57595
Quinn, G., Abdel Hameed, A., Banat, I., Berrar, D., Doerr, S., Dudley, E., Francis, L., Gazze, S., Hallin, I., Matthews, G., Swain, M., Whalley, W., & Van Keulen, G. (2022). Complementary protein extraction methods increase the identification of the Park Grass Experiment metaproteome. Applied Soil Ecology, 173, 104388
https://doi.org/10.1016/j.apsoil.2022.104388, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59232
TOUBHANS, B., Alkafri, N., Quintela Vazquez, M., James, D., Bissardon, C., Gazze, S., Knodel, F., Proux, O., Gourlan, A., Rathert, P., Bohic, S., Gonzalez, D., Francis, L., Charlet, L., & Conlan, S. (2023). Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion. Redox Biology, 61, 102641
https://doi.org/10.1016/j.redox.2023.102641, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62755
Bissardon, C., Proux, O., Gazze, S., Filhol, O., TOUBHANS, B., Sauzéat, L., Bouchet, S., Lewis, A., Maffeis, T., Hazemann, J., Bayat, S., Cloetens, P., Conlan, S., Charlet, L., & Bohic, S. (2023). Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells. Nanomaterials, 13(23), 2999
https://doi.org/10.3390/nano13232999, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65073
http://dx.doi.org/10.3390/nano13232999

Holl Ymchwil

Erthyglau Cylchgronau

Bissardon, C., Proux, O., Gazze, S., Filhol, O., TOUBHANS, B., Sauzéat, L., Bouchet, S., Lewis, A., Maffeis, T., Hazemann, J., Bayat, S., Cloetens, P., Conlan, S., Charlet, L., & Bohic, S. (2023). Intracellular Fate of Sub-Toxic Concentration of Functionalized Selenium Nanoparticles in Aggressive Prostate Cancer Cells. Nanomaterials, 13(23), 2999
https://doi.org/10.3390/nano13232999, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa65073
http://dx.doi.org/10.3390/nano13232999
TOUBHANS, B., Alkafri, N., Quintela Vazquez, M., James, D., Bissardon, C., Gazze, S., Knodel, F., Proux, O., Gourlan, A., Rathert, P., Bohic, S., Gonzalez, D., Francis, L., Charlet, L., & Conlan, S. (2023). Selenium nanoparticles modulate histone methylation via lysine methyltransferase activity and S-adenosylhomocysteine depletion. Redox Biology, 61, 102641
https://doi.org/10.1016/j.redox.2023.102641, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa62755
Quinn, G., Abdel Hameed, A., Banat, I., Berrar, D., Doerr, S., Dudley, E., Francis, L., Gazze, S., Hallin, I., Matthews, G., Swain, M., Whalley, W., & Van Keulen, G. (2022). Complementary protein extraction methods increase the identification of the Park Grass Experiment metaproteome. Applied Soil Ecology, 173, 104388
https://doi.org/10.1016/j.apsoil.2022.104388, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa59232
Edwards, K., Yao, S., Pisano, S., Feltracco, V., Bruesehafer, K., Samanta, S., Oommen, O., Gazze, S., Paravati, R., Maddison, H., Li, C., Gonzalez, D., Conlan, S., & Francis, L. (2021). Hyaluronic Acid-Functionalized Nanomicelles Enhance SAHA Efficacy in 3D Endometrial Cancer Models. Cancers, 13(16), 4032
https://doi.org/10.3390/cancers13164032, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa57595
Gazze, S., Thomas, S., Garcia-Parra, J., James, D., Rees, P., Marsh-Durban, V., Corteling, R., Gonzalez, D., Conlan, S., & Francis, L. (2021). High content, quantitative AFM analysis of the scalable biomechanical properties of extracellular vesicles. Nanoscale, 13(12), 6129-6141.
https://doi.org/10.1039/d0nr09235e, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa56477
Pisano, S., Wang, X., Garcia Parra, J., Gazze, S., Edwards, K., Feltracco, V., Hu, Y., He, L., Gonzalez, D., Francis, L., Conlan, S., & Li, C. (2020). Nanomicelles potentiate histone deacetylase inhibitor efficacy in vitro. Cancer Nanotechnology, 11(1)
https://doi.org/10.1186/s12645-020-00070-8, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa55789
Toubhans, B., Gazze, S., Bissardon, C., Bohic, S., Gourlan, A., Gonzalez, D., Charlet, L., Conlan, S., & Francis, L. (2020). Selenium nanoparticles trigger alterations in ovarian cancer cell biomechanics. Nanomedicine: Nanotechnology, Biology and Medicine, 29, 102258
https://doi.org/10.1016/j.nano.2020.102258, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54635
Friguglietti, J., Das, S., Le, P., Fraga, D., Quintela Vazquez, M., Gazze, S., McPhail, D., Gu, J., Sabek, O., Gaber, A., Francis, L., Zagozdzon-Wosik, W., & Merchant, F. (2020). Novel Silicon Titanium Diboride Micropatterned Substrates for Cellular Patterning. Biomaterials, 244, 119927
https://doi.org/10.1016/j.biomaterials.2020.119927, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa54548
Sawhney, M., Azzopardi, E., Rodrigues Teixeira, S., Francis, L., Conlan, R., Gazze, S., Conlan, S., & Gazze, S. (2019). Measuring the impact on impedance spectroscopy of pseudo-reference electrode accumulations. Electrochemistry Communications, 105, 106508
https://doi.org/10.1016/j.elecom.2019.106508, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa51355
Gazze, A., Ademefun, R., Conlan, R., Teixeira, S., Conlan, S., & Gazze, S. (2018). Electrochemical impedence spectroscopy enabled CA125 detection; toward early ovarian cancer diagnosis using graphene biosensors. Journal of Interdisciplinary Nanomedicine, 3(2), 82-88.
https://doi.org/10.1002/jin2.40, SU Repository: https://cronfa.swan.ac.uk/Record/cronfa43526

Hanes Gyrfa

Cynorthwyydd Ymchwil , Bilbao, Gwlad y Basg, Sbaen

2004 - Presennol

Grantiau a Phrosiectau Allweddol

ReNeuron, IgInnovations and Swansea University development of Exosomes towards clinical utility (RISE) 2018

Cyflwyniadau, Darlithoedd a Chynadleddau a wahoddwyd

Use of AFM for biogenic mineral dissolution and soil characterization

2017

Grenoble, Ffrainc